SynthesisHead and neck pathology2021
Metastasizing Ameloblastoma: A 10 Year Clinicopathological Review with an Insight Into Pathogenesis.
Synthesis in Head and neck pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Prevalence of Viruses in Odontogenic Cysts and Tumours:Sultan Qaboos University medical journal · 2025Pooled it
- Lung Metastatic Ameloblastoma: A Hidden Cause of Pulmonary Nodules.Balkan medical journal · 2026Article
- Spontaneous Bone Regeneration followed by Segmental Resection of Mandibular Unicystic Ameloblastoma with Primary Reconstruction in 12-Year-Old Girl: A Case Report.World journal of plastic surgery · 2026Article
- Metastasizing Ameloblastoma Mimicking Squamous Cell Carcinoma of the Lung and Harboring an AKT1 Mutation.Head and neck pathology · 2025Article
- Durable disease regression with copanlisib treatment in PI3K-mutated metastasizing ameloblastoma: A case report.Rare tumors · 2025Article
- Article
- Imaging approach for jaw and maxillofacial bone tumors with updates from the 2022 World Health Organization classification.World journal of radiology · 2024Review
- Metastasising ameloblastoma or ameloblastic carcinoma? A case report with mutation analyses.BMC oral health · 2023Review
- Conventional Ameloblastoma. A Case Report with Microarray and Bioinformatic Analysis.Diagnostics (Basel, Switzerland) · 2022Article
- Metastasizing ameloblastoma of the breast: A case report.International journal of surgery case reports · 2022Article
- Review
- Clinico-pathological and prognostic overview of metastasizing ameloblastoma: An overview of the systematic reviews.Journal of oral biology and craniofacial researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ameloblastoma, a benign but locally aggressive odontogenic tumor, often demonstrates metastasis despite benign histological features and this variant is termed as metastasizing ameloblastoma (METAM). It was classified under the malignant category in the 2005 WHO but has been re-classified under benign epithelial odontogenic tumors in the latest 2017 WHO classification. The present review aimed at gathering the available data on METAM to update the current cognizance about the pathology. Comprehensive search of the databases (viz., PubMed, Medline, SCOPUS, Web of Science, EMBASE and Google Scholar) was done for published articles on METAM following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A total of 42 cases were extracted. The mean age of occurrence was 42.71 ± 15.87 years. A slight male predilection was noted. Mandibular cases showed more metastasis than maxillary cases. Follicular ameloblastoma was most frequently encountered at secondary site followed by plexiform type. Lungs were the most commonly affected secondary sites. METAM is a rare odontogenic tumor and the diagnosis is usually made in retrospect. Inadequate treatment may result in multiple recurrences and metastasis in rare instances. Metastasis in ameloblastoma appears to be multi-factorial in nature and needs further investigation in untapped territory like exploration of quantum effects at cellular and molecular levels.
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