Evidence map›Paper›PMID 33394367›Full record

ArticleLa Radiologia medica2021

Dynamic contrast-enhanced magnetic resonance lymphangiography in pediatric patients with central lymphatic system disorders.

Veronica Bordonaro, Paolo Ciancarella, Paolo Ciliberti, Davide Curione, Carmela Napolitano, Teresa Pia Santangelo, Gian Luigi Natali, Massimo Rollo, Paolo Guccione, Luciano Pasquini and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Repeat misdiagnosis of chylous pneumonia: a case description.Quantitative imaging in medicine and surgery · 2026
    Article
  2. Complex lymphatic anomalies.Pediatric radiology · 2025
    Review
  3. EBUS/EUS-guided lymph nodal gadolinium injection and MRI of the chest in diagnosis of abnormal lymphatic drainage. A case series.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  4. Nodal Lymphangiography and Embolization for Postoperative Lymphatic Leakage.Interventional radiology (Higashimatsuyama-shi (Japan) · 2025
    Review
  5. Article
  6. Review
  7. Peritoneal Carcinosis: What the Radiologist Needs to Know.Diagnostics (Basel, Switzerland) · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Veronica BordonaroDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. veronica.bordonaro@opbg.net.ORCID http://orcid.org/0000-0002-9011-0793
Paolo CiancarellaDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Paolo CilibertiDepartment of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Davide CurioneDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Carmela NapolitanoDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Teresa Pia SantangeloDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Gian Luigi NataliDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Massimo RolloDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Paolo GuccioneDepartment of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Luciano PasquiniDepartment of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Aurelio SecinaroDepartment of Imaging, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Bambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central conducting lymphatics (CCLs) disorders represent a broad spectrum of clinical entities ranging from self-limiting traumatic leaks treated by conservative strategies, to complex lymphatic circulation abnormalities that are progressive and unresponsive to currently available treatments. Dynamic contrast-enhanced magnetic resonance lymphangiography (DCMRL) performed by intranodal injection of gadolinium-based contrast material is a recently developed technique which allows a minimally invasive evaluation of the CCL abnormalities providing a dynamic assessment of lymph flow and its pathways. In our institution, DCMRL is performed after bilateral cannulation of inguinal lymph nodes, using a MR protocol which includes volumetric 3D T2-SPACE (sampling perfection with application-optimized contrasts using different flip-angle evolution) and free-breathing respiratory navigated sequence and TWIST (time-resolved angiography with Interleaved stochastic trajectories) MR angiography sequence, during intranodal injection of paramagnetic contrast medium. Although DCMRL applications in clinical practice are still improving, a minimally invasive assessment of lymphatic pathways is particularly important both in pediatric patients with primitive lymphatic system disorders and in children with complex congenital heart disease associated with CCL impairment.

Indexed as

ChildContrast MediaFemaleHumansLymphatic DiseasesMagnetic Resonance ImagingMaleMeglumineOrganometallic CompoundsContrast Mediagadoterate meglumineMeglumineOrganometallic CompoundsCentral lymphatic systemLymphatic malformationMR lymphangiographyPlastic bronchitis

Identifiers

PMID33394367
OpenAlexW3119588604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.