Evidence map›Paper›PMID 33394366›Full record

ArticleLa Radiologia medica2021

Radiomic features for prostate cancer grade detection through formal verification.

Antonella Santone, Maria Chiara Brunese, Federico Donnarumma, Pasquale Guerriero, Francesco Mercaldo, Alfonso Reginelli, Vittorio Miele, Andrea Giovagnoni, Luca Brunese

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In one paragraph

Article in La Radiologia medica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Radiomics in Lung Metastases: A Systematic Review.Journal of personalized medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonella SantoneDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
Maria Chiara BruneseDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
Federico DonnarummaDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
Pasquale GuerrieroDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.
Francesco MercaldoDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy. francesco.mercaldo@unimol.it.ORCID http://orcid.org/0000-0002-9425-1657
Alfonso ReginelliDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", Napoli, Italy.
Vittorio MieleAOU Careggi University Hospital, Firenze, Italy.
Andrea GiovagnoniDepartment of Radiology, Ospedali Riuniti, Universit Politecnica delle Marche, Ancona, Italy.
Luca BruneseDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimProstate cancer represents the most common cancer afflicting men. It may be asymptomatic at the early stage. In this paper, we propose a methodology aimed to detect the prostate cancer grade by computing non-invasive shape-based radiomic features directly from magnetic resonance images. MATERIALS AND

methodsWe use a freely available dataset composed by coronal magnetic resonance images belonging to 112 patients. We represent magnetic resonance slices in terms of formal model, and we exploit model checking to check whether a set of properties (formulated with the support of pathologists and radiologists) is verified on the formal model. Each property is related to a different cancer grade with the aim to cover all the cancer grade groups.

resultsAn average specificity equal to 0.97 and an average sensitivity equal to 1 have been obtained with our methodology.

conclusionThe experimental analysis demonstrates the effectiveness of radiomics and formal verification for Gleason grade group detection from magnetic resonance.

Indexed as

Biopsy, NeedleDatasets as TopicHumansMagnetic Resonance ImagingMaleNeoplasm GradingPredictive Value of TestsProstatic NeoplasmsSensitivity and SpecificityFormal methodsGleason grade groupModel checkingProstateRadiomics

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.