Evidence map›Paper›PMID 33394351›Full record

ReviewVirologica Sinica2020

Human Monoclonal Antibodies: On the Menu of Targeted Therapeutics Against COVID-19.

Junsen Chen, Rui Huang, Yiwen Nie, Xinyue Wen, Ying Wu

Open access · bronzeAbstract readReview
In one paragraph

Review in Virologica Sinica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Junsen ChenState Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430072, China.
Rui HuangState Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430072, China.
Yiwen NieState Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430072, China.
Xinyue WenState Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430072, China.
Ying WuState Key Laboratory of Virology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430072, China. yingwu@whu.edu.cn.ORCID http://orcid.org/0000-0002-2716-6209
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), reminiscent of the severe acute respiratory syndrome (SARS) outbreak in 2003, has been a tragic disaster to people all over the world. As there is no specific drug for COVID-19, neutralizing antibodies are attracting more and more attention as one of the most effective means to combat the pandemic. Here, we introduced the etiological and serological characteristics of COVID-19, discussed the current stage of development of human monoclonal antibodies against SARS-CoV-2 and summarized the antigenic epitopes in the S glycoprotein, which may deepen the understanding of the profile of immune recognition and response against SARS-CoV-2 and provide insight for the design of effective vaccines and antibody-based therapies.

Indexed as

COVID-19 Drug TreatmentAnimalsAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralAntigens, ViralCOVID-19EpitopesHumansNeutralization TestsPandemicsSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralAntigens, ViralEpitopesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2COVID-19EpitopesmAbsS glycoprotein

Identifiers

PMID33394351
PMCPMC7779898
OpenAlexW3120437566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.