Evidence map›Paper›PMID 33394316›Full record

ArticleJournal of clinical immunology2021

Uncontrolled Epstein-Barr Virus as an Atypical Presentation of Deficiency in ADA2 (DADA2).

Joel P Brooks, Andrew J Rice, Weizhen Ji, Stephen M Lanahan, Monica Konstantino, Jasmeen Dara, Michael S Hershfield, Amy Cruickshank, Elif Dokmeci, Saquib Lakhani and 1 more

Abstract readCase ReportsLetter
PubMed Publisher
In one paragraph

Article in Journal of clinical immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Human ADA2 Deficiency: Ten Years Later.Current allergy and asthma reports · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joel P Brooks *Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Andrew J Rice *Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Weizhen JiPediatric Genomics Discovery Program, Yale University School of Medicine, New Haven, CT, USA.
Stephen M LanahanDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Monica KonstantinoPediatric Genomics Discovery Program, Yale University School of Medicine, New Haven, CT, USA.
Jasmeen DaraDivision of Pediatric Allergy, Immunology, and Bone Marrow Transplantation, University of California San Francisco, Benioff Children's Hospital, San Francisco, CA, USA.
Michael S HershfieldDepartment of Medicine, Duke University School of Medicine, Durham, NC, USA.
Amy CruickshankDepartment of Pediatrics, University of New Mexico, Albuquerque, NM, USA.
Elif DokmeciDepartment of Pediatrics, University of New Mexico, Albuquerque, NM, USA.
Saquib LakhaniPediatric Genomics Discovery Program, Yale University School of Medicine, New Haven, CT, USA. Saquib.Lakhani@yale.edu.
Carrie L LucasDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. Carrie.Lucas@yale.edu.ORCID 0000-0002-5754-0820

Funding

INTERDISCIPLINARY IMMUNOLOGY TRAINING PROGRAMT32AI007019 · NIAID · YALE UNIVERSITY · PI Carrie L. Lucas, David G. Schatz · 1985 to 2026
$14.4M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenosine DeaminaseAntiviral AgentsBiomarkersBiopsyChildDisease ManagementDisease SusceptibilityDNA Mutational AnalysisEpstein-Barr Virus InfectionsExome SequencingFemaleHematopoietic Stem Cell TransplantationHumansIntercellular Signaling Peptides and ProteinsSevere Combined ImmunodeficiencySiblingsADA2 protein, humanAdenosine DeaminaseAntiviral AgentsBiomarkersIntercellular Signaling Peptides and Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.