Evidence map›Paper›PMID 33394280›Full record

Observational studyInternational urology and nephrology2021

Comparison of nutritional and hydration status in patients undergoing twice and thrice-weekly hemodialysis: a silent drama in developing countries.

Iris Nieves-Anaya, M B Várgas, H Mayorga, O P García, E Colín-Ramírez, X Atilano-Carsi

Registry-linked trialAbstract readComparative StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in International urology and nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05288101 (Effect of Oral Nutritional Supplementation Combined With Impedance Vectors for Dry Weight Adjustment on the Nutritional Status, Hydration Status and Quality of Life in Patients on Chronic Hemodialysis), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05288101 nacompletednot on this map

Effect of Oral Nutritional Supplementation Combined With Impedance Vectors for Dry Weight Adjustment on the Nutritional Status, Hydration Status and Quality of Life in Patients on Chronic Hemodialysis: a Pilot Study

TypeinterventionalSponsorUniversidad Autonoma de QueretaroRan2017 to 2017Enrolled39ConditionsChronic Kidney Disease Requiring Chronic Dialysis, Overhydration, UndernutritionArmsProteinex and Enterex DBT Victus Laboratories, Dry weight adjustment through BIVA
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Impact of incremental initiation of haemodialysis on mortality: a systematic review and meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Iris Nieves-AnayaFacultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Juriquilla, México.
M B VárgasFacultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Juriquilla, México.
H MayorgaNephrology and Dialysis Unit, Querétaro, México.
O P GarcíaFacultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Juriquilla, México.ORCID https://orcid.org/0000-0003-4040-8345
E Colín-RamírezFaculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, T6G 2E1, Canada.
X Atilano-CarsiDepartamento de Nefrología y Metabolismo Mineral, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Col. Sección XVI, Delegación Tlalpan, Ciudad de México, 14000, México. xime1879@hotmail.com.ORCID http://orcid.org/0000-0002-6702-1688

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn low and middle- income countries, due to lack of financial resources, the number of patients receiving one or two hemodialysis (HD) sessions a week has increased, leading to a large number of complications. Protein-energy wasting (PEW) and overhydration (OH) are common complications; nevertheless, the evidence regarding the nutritional status of patients receiving 2 and 3 weekly dialysis sessions is scarce. Thus, our objective was to compare the nutritional and hydration status of patients with two and three HD sessions. Secondarily, we aimed to compare hospitalizations, infectious complications and mortality within the following 6 months after the initial assessment.

methodsForty-four patients in a 3 weekly session scheme and 44 dialyzed twice a week were included. Anthropometrical, biochemical, dietary and impedance measurements were performed. Malnutrition Inflammation Score (MIS) and PEW score were applied. Number of hospitalizations, infectious complications and mortality during the 6 months following the evaluation were recorded.

resultsPrevalence of moderate/severe undernutrition (63.6% vs 36.4%, p < 0.006) and prevalence of OH (90.9% vs 77.3%, p < 0.001) were significantly higher in the twice-weekly sessions group compared to the 3 weekly sessions. The twice a week session group showed a 3.7-fold (OR 3.7, 95% CI 1.3-10.5, p = 0.01), a 2.5-fold (OR 2.4, 95% CI 0.9-6.6, p = 0.01), a 4.5-fold (OR 4.5, 95% CI 1.0-20.2, p < 0.05), a 8.3-fold (HR 8.3, 95% CI 2.4-28.2, p = 0.001) and a 11.6-fold (HR 11.6, 95% CI 2.4-54.0, p = 0.002) increased odds of developing undernutrition, PEW, OH, being hospitalized or death, respectively, compared to those who received three sessions per week.

conclusionsTwice weekly hemodialysis scheme is associated with higher odds of moderate or severe undernutrition, PEW, OH status, hospitalization and mortality compared to a thrice-weekly hemodialysis scheme.

Indexed as

AdultAgedDeveloping CountriesFemaleHumansMaleMiddle AgedNutritional StatusProtein-Energy MalnutritionRenal DialysisWater-Electrolyte ImbalanceBody compositionHemodialysisHydration statusImpedance vectorsProtein-energy wasting

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.