Evidence map›Paper›PMID 33394254›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2022

Abdominal wound dehiscence is dangerous: a nationwide study of 14,169 patients undergoing elective open resection for colonic cancer.

K K Jensen, E Oma, G H van Ramshorst, A Nordholm-Carstensen, P-M Krarup

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06501508 (Abdominal Wall Dehiscence After Laparotomy Closure in Abdominal Surgery), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06501508 unknown statusnot on this mapstarted 2023, after this paper: background citation

Abdominal Wall Dehiscence After Laparotomy Closure in Abdominal Surgery: a Retrospective Observational Study on the Influence of the Suture Used

TypeobservationalSponsorInstituto de Investigación Sanitaria de la Fundación Jiménez DíazRan2023 to 2024Enrolled1,900ConditionsSurgical Wound DehiscenceArmsStratafix Symmetric
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Article
  3. Early outcomes of contaminated midline incisional hernia repair with mesh suture.Hernia : the journal of hernias and abdominal wall surgery · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Abdominal fascia dehiscence: is there a connection to a special microbial spectrum?Hernia : the journal of hernias and abdominal wall surgery · 2023
    Article
  9. Defining High-Risk Patients Suitable for Incisional Hernia Prevention.Journal of abdominal wall surgery : JAWS · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

K K JensenDigestive Disease Center, Bispebjerg University Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark. mail@kristiankiim.dk.ORCID http://orcid.org/0000-0003-4212-4936
E OmaDigestive Disease Center, Bispebjerg University Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.
G H van RamshorstDepartment of Gastrointestinal Surgery, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Gent, Belgium.
A Nordholm-CarstensenDigestive Disease Center, Bispebjerg University Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.
P-M KrarupDigestive Disease Center, Bispebjerg University Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.
University of Copenhagen · DKGhent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe potential impact of abdominal wound dehiscence on long-term survival after elective abdominal surgery is largely unknown. The aim of this study was to examine the impact of abdominal wound dehiscence on survival and incisional hernia repair after elective, open colonic cancer resection.

methodsThis was a nationwide cohort study based on merged data from Danish national registries, comprising patients subjected to elective, open resection for colonic cancer between May 1, 2001 and January 1, 2016. Multivariable Cox Regression analysis and propensity score matching was applied to adjust for confounding. The associations of abdominal wound dehiscence with 90-day mortality and subsequent incisional hernia repair were also examined.

resultsA total of 14,169 patients were included in the cohort, of which 549 (3.9%) developed abdominal wound dehiscence. The 5-year survival was significantly decreased in patients with abdominal wound dehiscence (42.4%, 95% CI 38.1-46.7 vs. 53.4%, 52.6-54.3, P < 0.001), which was confirmed in the multivariable analysis (HR 1.22, CI 1.06-1.39, P = 0.004). Abdominal wound dehiscence was significantly associated with increased risk of 90-day mortality (OR 1.60, CI 1.12-2.27, P = 0.009) as well as subsequent incisional hernia repair (HR 1.80, CI 1.07-3.01, P = 0.026).

conclusionsAbdominal wound dehiscence was significantly associated with decreased survival. Fascial closure after open colonic cancer resection should be given high priority to improve the long-term survival.

Indexed as

Abdominal InjuriesColonic NeoplasmsHernia, VentralIncisional HerniaCohort StudiesFollow-Up StudiesHerniorrhaphyHumansPostoperative ComplicationsSurgical Wound DehiscenceBurst abdomenColonic cancerFascial dehiscenceMortalityWound complication

Identifiers

PMID33394254
OpenAlexW3119395133

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.