Evidence map›Paper›PMID 33394208›Full record

ArticleCancer causes & control : CCC2021

Adherence to annual lung cancer screening with low-dose CT scan in a diverse population.

Cherie P Erkmen, Farouk Dako, Ryan Moore, Chandra Dass, Mark G Weiner, Larry R Kaiser, Grace X Ma

Abstract read
In one paragraph

Article in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Improving lung cancer screening diagnostic efficiency.Current opinion in pulmonary medicine · 2026
    Review
  6. Review
  7. Updates in Lung Cancer Screening: A Decade of Evidence.Seminars in respiratory and critical care medicine · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Dismal adherence to lung cancer screening in a diverse urban population.The Journal of thoracic and cardiovascular surgery · 2025
    Article
  12. Article
  13. Pack-Year Smoking History: An Inadequate and Biased Measure to Determine Lung Cancer Screening Eligibility.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Article
  14. Article
  15. Review
  16. Death by a thousand delays.JTCVS open · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Disparities in thoracic surgical oncology.Journal of surgical oncology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cherie P ErkmenDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Parkinson Pavilion, Zone C, Suite 501, 3401 N. Broad Street, Philadelphia, PA, 19140, USA.
Farouk DakoDepartment of Radiology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA.
Ryan MooreDepartment of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, USA.
Chandra DassDepartment of Radiology, Lewis Katz School of Medicine at Temple University, Philadelphia, USA.
Mark G WeinerDepartment of Clinical Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, USA.
Larry R KaiserDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Parkinson Pavilion, Zone C, Suite 501, 3401 N. Broad Street, Philadelphia, PA, 19140, USA.
Grace X MaDepartment of Clinical Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, USA. grace.ma@temple.edu.

Funding

TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221705 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI GRACE X. MA · 2018 to 2026
$16.3M
TUFCCC/HC Regional Comprehensive Cancer Health PartnershipU54CA221704 · NCI · HUNTER COLLEGE · PI Joel Erblich, Jennifer S Ford · 2018 to 2026
$10.6M
NCI NIH HHS U54 CA221704NCI NIH HHS U54 CA221704(5)NCI NIH HHS U54 CA221705
6 · The paper itself

Abstract

purposeOur aim was to develop a novel approach for lung cancer screening among a diverse population that integrates the Centers for Medicare and Medicaid Services (CMS) recommended components including shared decision making (SDM), low-dose CT (LDCT), reporting of results in a standardized format, smoking cessation, and arrangement of follow-up care.

methodsBetween October of 2015 and March of 2018, we enrolled patients, gathered data on demographics, delivery of SDM, reporting of LDCT results using Lung-RADS, discussion of results, and smoking cessation counseling. We measured adherence to follow-up care, cancer diagnosis, cancer treatment, and smoking cessation at 2 years after initial LDCT.

resultsWe enrolled 505 patients who were 57% African American, 30% Caucasian, 13% Hispanic, < 1% Asian, and 61% were active smokers. All participants participated in SDM, 88.1% used a decision aid, and 96.1% proceeded with LDCT. Of 496 completing LDCT, all received a discussion about results and follow-up recommendations. Overall, 12.9% had Lung-RADS 3 or 4, and 3.2% were diagnosed with lung cancer resulting in a false-positive rate of 10.7%. All 48 patients with positive screens but no cancer diagnosis adhered to follow-up care at 1 year, but only 35.4% adhered to recommended follow-up care at 2 years. The annual follow-up for patients with negative lung cancer screening results (Lung-RADS 1 and 2) was only 23.7% after one year and 2.8% after 2 years. All active smokers received smoking cessation counseling, but only 11% quit smoking.

conclusionThe findings show that an integrated lung cancer screening program can be safely implemented in a diverse population, but adherence to annual screening is poor.

Indexed as

AgedEarly Detection of CancerFemaleHumansLung NeoplasmsMaleMass ScreeningMedicareMiddle AgedPatient ComplianceSmokingSmoking CessationTomography, X-Ray ComputedUnited StatesAdherence to lung cancer screeningAfrican AmericanDiverse populationLow-dose CT scanLung cancer screening

Identifiers

PMID33394208
PMCPMC7878339

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.