Evidence map›Paper›PMID 33394206›Full record

SynthesisCancer causes & control : CCC2021

The current burden of non-melanoma skin cancer attributable to ultraviolet radiation and related risk behaviours in Canada.

Dylan E O'Sullivan, Darren R Brenner, Paul J Villeneuve, Stephen D Walter, Paul A Demers, Christine M Friedenreich, Will D King, ComPARe Study Team

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. The effects of exposure to solar radiation on human health.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023
    Article
  8. Observational
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Dylan E O'SullivanDepartment of Public Health Sciences, Queen's University, Carruthers Hall, 62 Fifth Field Company Lane 2nd floor, Kingston, ON, K7L 3N6, Canada.ORCID http://orcid.org/0000-0002-2562-0017
Darren R BrennerDepartment of Cancer Epidemiology and Prevention Research, Alberta Health Services, CancerControl Alberta, Calgary, AB, Canada.
Paul J VilleneuveSchool of Mathematics and Statistics, Carleton University, Ottawa, ON, Canada.
Stephen D WalterDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.
Paul A DemersOccupational Cancer Research Centre, Ontario Health, Toronto, ON, Canada.
Christine M FriedenreichDepartment of Cancer Epidemiology and Prevention Research, Alberta Health Services, CancerControl Alberta, Calgary, AB, Canada.
Will D KingDepartment of Public Health Sciences, Queen's University, Carruthers Hall, 62 Fifth Field Company Lane 2nd floor, Kingston, ON, K7L 3N6, Canada. kingw@queensu.ca.
ComPARe Study Team
Alberta Health Services · CAQueen's University · CACarleton University · CAImpact · CAOccupational Cancer Research Centre · CA

Funding

Canadian Cancer Society #703106
6 · The paper itself

Abstract

purposeUltraviolet radiation (UVR) is an established cause of non-melanoma skin cancer (NMSC)-basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The aim of this study was to estimate the current burden of BCC and SCC associated with UVR and modifiable UVR behaviours (sunburn, sunbathing, and indoor tanning) in Canada in 2015.

methodsThe current burden of BCC and SCC associated with UVR was estimated by comparing 2015 incidence rates with rates of less exposed body sites (trunk and lower limbs) after adjusting for estimated surface areas. The burden associated with modifiable UVR behaviours was estimated by using prevalence estimates among Caucasians from the Second National Sun Survey, and relative risks that are generalizable to Canadians from conducting meta-analyses of relevant studies.

resultsWe estimated that 80.5% of BCCs and 83.0% of SCCs were attributable to UVR. Adult sunburn was associated with relative risks of 1.85 (95% CI 1.15-3.00) for BCC and 1.41 (95% CI 0.91-2.18) for SCC, while adult sunbathing was associated with relative risks of 1.82 (95% CI 1.52-2.17) for BCC and 1.14 (95% CI 0.53-2.46) for SCC. We estimated that 18.6% of BCCs and 9.9% of SCCs were attributable to adult sunburn, while 28.1% of BCCs were attributable to adult sunbathing. We estimated that 46.2% of BCCs and 17.3% of SCCs were attributable to modifiable UVR behaviours combined.

conclusionOur results provide quantifiable estimates of the potentially avoidable burden of NMSCs among Canadians. These estimates can be used to motivate prevention efforts in Canada.

Indexed as

AgedBasal Cell CarcinomaCanadaCarcinoma, Squamous CellFemaleHumansIncidenceMaleMiddle AgedRiskRisk-TakingSkin NeoplasmsSunbathingSunburnUltraviolet RaysBasal cell carcinomaCutaneous squamous cell carcinomaNon-melanoma skin cancerPopulation attributable riskSun behavioursUltraviolet radiation

Identifiers

PMID33394206
OpenAlexW3120896118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.