Evidence map›Paper›PMID 33394204›Full record

ArticleCancer causes & control : CCC2021

Men's experiences of radiotherapy treatment for localized prostate cancer and its long-term treatment side effects: a longitudinal qualitative study.

E Sutton, J A Lane, M Davis, E I Walsh, D E Neal, F C Hamdy, M Mason, J Staffurth, R M Martin, C Metcalfe and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Relationship Values and Committed Actions Among Couples Coping with Prostate Cancer: A Qualitative Study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  8. Impact of Treatment Modality on Quality of Life Among Uterine Cancer Survivors.Clinical oncology (Royal College of Radiologists (Great Britain)) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

E Sutton *Department of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK.ORCID http://orcid.org/0000-0003-4105-8471
J A LaneDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK.
M DavisDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK.
E I WalshDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK.
D E NealNuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
F C HamdyNuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
M MasonDivision of Cancer & Genetics, School of Medicine, Cardiff University, Cardiff, UK.
J StaffurthDepartment of Oncology, Cardiff University, Cardiff, UK.
R M MartinDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK.
C MetcalfeDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK.
T J PetersDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK.
J L DonovanDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK.
J Wade *Department of Population Health Sciences, Bristol Medical School, University of Bristol, Canynge Hall, Bristol, UK. julia.wade@bristol.ac.uk.
ProtecT Study Group
University of Bristol · GBAt Bristol · GBNational Institute for Health Research · GBUniversity of Oxford · GBCardiff University · GB

Funding

Health Technology Assessment Programme 96/20/06Health Technology Assessment Programme 96/20/99Medical Research Council MR/K025643/1
6 · The paper itself

Abstract

purposeTo investigate men's experiences of receiving external-beam radiotherapy (EBRT) with neoadjuvant Androgen Deprivation Therapy (ADT) for localized prostate cancer (LPCa) in the ProtecT trial.

methodsA longitudinal qualitative interview study was embedded in the ProtecT RCT. Sixteen men with clinically LPCa who underwent EBRT in ProtecT were purposively sampled to include a range of socio-demographic and clinical characteristics. They participated in serial in-depth qualitative interviews for up to 8 years post-treatment, exploring experiences of treatment and its side effects over time.

resultsMen experienced bowel, sexual, and urinary side effects, mostly in the short term but some persisted and were bothersome. Most men downplayed the impacts, voicing expectations of age-related decline, and normalizing these changes. There was some reticence to seek help, with men prioritizing their relationships and overall health and well-being over returning to pretreatment levels of function. Some unmet needs with regard to information about treatment schedules and side effects were reported, particularly among men with continuing functional symptoms.

conclusionsThese findings reinforce the importance of providing universal clear, concise, and timely information and supportive resources in the short term, and more targeted and detailed information and care in the longer term to maintain and improve treatment experiences for men undergoing EBRT.

Indexed as

AgedAndrogen AntagonistsCombined Modality TherapyHumansLongitudinal StudiesMaleMiddle AgedProstatic NeoplasmsQualitative ResearchRadiation InjuriesSurveys and QuestionnairesAndrogen AntagonistsExternal-beam radiotherapyProstate cancerQualitative researchRadiotherapyTreatment experiencesTreatment side effects

Identifiers

PMID33394204
PMCPMC7870600
OpenAlexW3120134485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.