Evidence map›Paper›PMID 33394059›Full record

ReviewHerz2021

Valvular heart disease in patients with chronic kidney disease.

Julian Hoevelmann, Felix Mahfoud, Lucas Lauder, Bruno Scheller, Michael Böhm, Sebastian Ewen

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Herz, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06660524 (Clinical Study on the Influence of Calcium and Phosphorus Regulation Therapy on Valvular Heart Disease.), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06660524 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Study on the Influence of Calcium and Phosphorus Regulation Therapy on Valvular Heart Disease.

TypeinterventionalSponsorChina National Center for Cardiovascular DiseasesRan2024 to 2025Enrolled196ConditionsDegenerative Heart Valve Disease, Heart Valve Calcification, Chronic Kidney Disease(CKD), Calcium-Phosphorus Metabolism DisordersArmsSevelamer, Calcium carbonate
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
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  6. Article
  7. Article
  8. Review
  9. Article
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  11. Article
  12. The influence of renal disease on outcomes and cardiac remodeling following surgical mitral valve replacement.Clinical research in cardiology : official journal of the German Cardiac Society · 2023
    Article
  13. Review
  14. Regression Models to Study the Total LOS Related to Valvuloplasty.International journal of environmental research and public health · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Cardiac Involvement in Chronic Kidney Disease: Epidemiology, Pathophysiology, and Complications.Heart views : the official journal of the Gulf Heart Association
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Julian HoevelmannKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Saarland University Hospital, Kirrberger Str., IMED, 66421, Homburg/Saar, Germany. Julian.hoevelmann@uks.eu.
Felix MahfoudKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Saarland University Hospital, Kirrberger Str., IMED, 66421, Homburg/Saar, Germany.
Lucas LauderKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Saarland University Hospital, Kirrberger Str., IMED, 66421, Homburg/Saar, Germany.
Bruno SchellerKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Saarland University Hospital, Kirrberger Str., IMED, 66421, Homburg/Saar, Germany.
Michael BöhmKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Saarland University Hospital, Kirrberger Str., IMED, 66421, Homburg/Saar, Germany.
Sebastian EwenKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Saarland University Hospital, Kirrberger Str., IMED, 66421, Homburg/Saar, Germany.
Saarland University · DEUniversitätsklinikum des Saarlandes · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Valvular heart disease (VHD) is common in patients with impaired renal function, especially in those with end-stage renal disease (ESRD) undergoing dialysis. Progressive sclerosis and calcification of the valves and valvular annuli are major components of the etiology. These processes typically affect the aortic and mitral valve and can lead to both valvular insufficiency and stenosis. As recommended by the 2017 ESC/EACTS Guidelines for the management of VHD, surgical treatment remains the standard care for most cases of severe VHD. However, chronic kidney disease (CKD) is associated with increased mortality when compared with patients with preserved renal function. Interventional treatment options have emerged as an effective and safe alternative for patients older than 75 years and/or with increased surgical risk. Consequently, in patients with CKD at increased surgical risk who have suitable anatomical morphology, transcatheter replacement and/or repair should be discussed in the interdisciplinary "heart team."

Indexed as

Aortic Valve StenosisCalcinosisHeart Valve DiseasesKidney Failure, ChronicRenal Insufficiency, ChronicHumansMitral ValveCardiovascular diseaseInterventional treatment optionsMitraClipTMRenal insufficiency, chronicTranscatheter aortic valve replacement

Identifiers

PMID33394059
OpenAlexW3119758876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.