ArticleJMIR perioperative medicine2019
The Trendelenburg Position and Cognitive Decline: A Case-Control Interventional Study Involving Healthy Volunteers.
Article in JMIR perioperative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Influence of steep Trendelenburg position on postoperative complications: a systematic review and meta-analysis.Journal of robotic surgery · 2022Pooled it
- Neck extension during thyroidectomy: effects on early postoperative cognitive function and optic nerve sheath diameter- a randomized controlled trial.BMC anesthesiology · 2025Trial
- [Anesthesia for robot-assisted surgery].Die Anaesthesiologie · 2026Review
- Complication Rates are Low for Women Aged 70 and Older Undergoing Sacrocolpopexy.International urogynecology journal · 2025Article
- Effect of Intravenous Lidocaine on Postoperative Cognitive Dysfunction in Patients Undergoing Laparoscopic Colorectal Surgery: A Two-Center, Randomized, Double-Blind Controlled Trial.Current therapeutic research, clinical and experimental · 2025Article
- Mesial temporal atrophy in preoperative MRI rather than steep Trendelenburg position is associated with postoperative delirium in patients undergoing a major urologic surgery.International urology and nephrology · 2024Article
- Robot-assisted supratrigonal cystectomy and augmentation cystoplasty for adult neurogenic lower urinary tract dysfunction: comparison of extracorporeal versus intracorporeal diversion.Therapeutic advances in urologyArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative cognitive decline (POCD) is defined as a new cognitive impairment arising after a surgical intervention. Aspects of cognitive function can be assessed using various validated cognitive function tests including the N-back task, the Stroop task, and the lexical decision-making task (LDT). There is some concern that prolonged Trendelenburg positioning during laparoscopic colorectal surgery may cause POCD.
objectiveThe objective of this study was to assess the effect of time spent in the Trendelenburg position on cognitive function.
methodsVolunteers were placed in the Trendelenburg position for 3 hours and, then, supine for 30 minutes. Validated cognitive function tests including 1-, 2-, and 3-back tasks, Stroop test, and LDT were performed at baseline and every 30 minutes after Trendelenburg positioning. Cognitive decline was defined per the International Study of Postoperative Cognitive Dysfunction trial: a decrease in accuracy from the volunteers' baseline or an increase in response time from the volunteers' baseline by >2 control group SDs.
resultsWe recruited 15 healthy volunteers (8 males, 7 females) with an average age of 69 years (range 57-81) and average body mass index of 27.7 kg/m
conclusionsThe results of this study indicate that Trendelenburg positioning leads to cognitive decline. This may have implications for patients undergoing prolonged Trendelenburg positioning during laparoscopic colorectal surgery.
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