Evidence map›Paper›PMID 33393859›Full record

ArticleThe neuroradiology journal2021

Association between cervical disc disease and lesions of multiple sclerosis.

Marwan Alkrenawi, Michael Osherov, Azaria Simonovich, Jonathan Droujin, Ron Milo, Shmuel Appel

Open access · greenAbstract read
In one paragraph

Article in The neuroradiology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marwan AlkrenawiDepartment of Neurology, Barzilai University Medical Centre, Israel.
Michael OsherovDepartment of Neurology, Barzilai University Medical Centre, Israel.
Azaria SimonovichDepartment of Radiology, Barzilai University Medical Centre, Israel.
Jonathan DroujinDepartment of Radiology, Barzilai University Medical Centre, Israel.
Ron MiloDepartment of Neurology, Barzilai University Medical Centre, Israel.
Shmuel AppelDepartment of Neurology, Barzilai University Medical Centre, Israel.ORCID https://orcid.org/0000-0003-1447-2183
Barzilai Medical Center · ILBen-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical discopathy and demyelinating lesions often co-exist in patients with multiple sclerosis (MS). Our study examines the possible association between these two pathologies.

methodsMedical records and cervical magnetic resonance imaging scans of MS patients with cervical discopathy who were seen at our MS clinic during 2018 were retrospectively reviewed. The severity of the disc disease was classified as grade I (no compression), grade II (compression of the dural sac) and grade III (cord compression). The spinal cord in each scan was divided into six segments corresponding to the intervertebral space of the spine (C1-C6). Each segment was defined as containing demyelinating lesion and disc pathology (group 1), demyelinating lesion without disc pathology (group 2), disc pathology without demyelinating lesion (group 3) and no demyelinating lesion or disc pathology (group 4). Fisher's exact test was used to test the association between demyelinating lesions and disc pathology.

resultsThirty-four MS patients with cervical discopathy were included in the study (26 females; average age 42.9 ± 13.7 years; average disease duration 8.4 ± 5.4 years). A total of 204 spinal cord segments were evaluated. Twenty-four segments were classified as group 1, 27 segments as group 2, 52 segments as group 3 and 101 segments as group 4. There was no association between demyelinating lesions and the grade of disc disease (

conclusionOur study did not find any association between cervical disc disease and demyelinating spinal cord lesion.

Indexed as

AdultCervical VertebraeFemaleHumansIntervertebral Disc DegenerationIntervertebral Disc DisplacementMagnetic Resonance ImagingMaleMultiple SclerosisRetrospective StudiesSeverity of Illness Indexcervical spondylitic myelopathydiscopathyMultiple sclerosisplaque

Identifiers

PMID33393859
PMCPMC8165899
OpenAlexW3120689981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.