Evidence map›Paper›PMID 33393839›Full record

ArticleCell adhesion & migration2021

Keratin 19 maintains E-cadherin localization at the cell surface and stabilizes cell-cell adhesion of MCF7 cells.

Sarah Alsharif, Pooja Sharma, Karina Bursch, Rachel Milliken, Van Lam, Arwa Fallatah, Thuc Phan, Meagan Collins, Priya Dohlman, Sarah Tiufekchiev and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cell adhesion & migration, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Sarah AlsharifDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.
Pooja SharmaDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.ORCID 0000-0002-6359-5043
Karina BurschDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.ORCID 0000-0001-6270-1716
Rachel MillikenDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.
Van LamDepartment of Biomedical Engineering, The Catholic University of America , Washington, District of Columbia, USA.
Arwa FallatahDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.ORCID 0000-0002-2366-0322
Thuc PhanDepartment of Electrical Engineering, The Catholic University of America , Washington, District of Columbia, USA.ORCID 0000-0003-3267-1100
Meagan CollinsDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.
Priya DohlmanDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.
Sarah TiufekchievDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.
Georges NehmetallahDepartment of Electrical Engineering, The Catholic University of America , Washington, District of Columbia, USA.ORCID 0000-0002-6918-4245
Christopher B RaubDepartment of Biomedical Engineering, The Catholic University of America , Washington, District of Columbia, USA.ORCID 0000-0001-9487-0979
Byung Min ChungDepartment of Biology, The Catholic University of America , Washington, District of Columbia, USA.ORCID 0000-0003-1262-5107
University of America · US

Funding

Mechanism and Impact of an Interaction Between Keratin 19 and a Regulator of Gene ExpressionR15CA213071 · NCI · CATHOLIC UNIVERSITY OF AMERICA · PI CHUNG, BYUNG MIN · 2018 to 2018
$473k
A dual-modality quantitative phase and polarized light microscope to assess cell motility and extracellular matrix remodeling during invasionR03EB028017 · NIBIB · CATHOLIC UNIVERSITY OF AMERICA · PI RAUB, CHRISTOPHER B · 2019 to 2020
$159k
NCI NIH HHS R15 CA213071NIBIB NIH HHS R03 EB028017
6 · The paper itself

Abstract

A cytoskeletal protein keratin 19 (K19) is highly expressed in breast cancer but its effects on breast cancer cell mechanics are unclear. In MCF7 cells where K19 expression is ablated,

Indexed as

CadherinsKeratin-19Cell AdhesionCell MembraneHumansMCF-7 CellsCadherinsKeratin-19KRT19 protein, humanadherens junctionbreast cancercell-cell adhesioncell migrationcell morphologyIntermediate filamentskeratinkeratin 19metastasis

Identifiers

PMID33393839
PMCPMC7801129
OpenAlexW3120207869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.