Evidence map›Paper›PMID 33393725›Full record

ArticlePhysiological reports2021

Prior oxygenation, but not chemoreflex responsiveness, determines breath-hold duration during voluntary apnea.

Christina D Bruce, Emily R Vanden Berg, Jamie R Pfoh, Craig D Steinback, Trevor A Day

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Christina D BruceDepartment of Biology, Faculty of Science and Technology, Mount Royal University, Calgary, AB, Canada.
Emily R Vanden BergDepartment of Biology, Faculty of Science and Technology, Mount Royal University, Calgary, AB, Canada.
Jamie R PfohDepartment of Biology, Faculty of Science and Technology, Mount Royal University, Calgary, AB, Canada.
Craig D SteinbackFaculty of Kinesiology, Sport, and Recreation, University of Alberta, Edmonton, AB, Canada.
Trevor A DayDepartment of Biology, Faculty of Science and Technology, Mount Royal University, Calgary, AB, Canada.ORCID 0000-0001-7102-4235
Mount Royal University · CAUniversity of Alberta · CAInterior Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central and peripheral respiratory chemoreceptors are stimulated during voluntary breath holding due to chemostimuli (i.e., hypoxia and hypercapnia) accumulating at the metabolic rate. We hypothesized that voluntary breath-hold duration (BHD) would be (a) positively related to the initial pressure of inspired oxygen prior to breath holding, and (b) negatively correlated with respiratory chemoreflex responsiveness. In 16 healthy participants, voluntary breath holds were performed under three conditions: hyperoxia (following five normal tidal breaths of 100% O

Indexed as

AdultApneaBreath HoldingChemoreceptor CellsFemaleHumansHypercapniaHypoxiaLungMaleOxygenReflexOxygenbreath-hold durationhypoxic ventilatory responseoxygenperipheral respiratory chemoreflexrespiratory chemoreceptorssteady-state chemoreflex drive

Identifiers

PMID33393725
PMCPMC7780234
OpenAlexW3120209798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.