ArticleChest2021
Trends and Geographic Variation in Acute Respiratory Failure and ARDS Mortality in the United States.
Article in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Long-term lung function recovery after ECMO versus non-ECMO management in acute respiratory failure: a systematic review and meta-analysis.BMC pulmonary medicine · 2024Pooled it
- Differences in the Response to High-Dose Inhaled Nitric Oxide in Self-identified Black and White Individuals: AAmerican journal of respiratory and critical care medicine · 2024Trial
- Inhaled prostacyclin therapy in the acute respiratory distress syndrome: a randomized controlled multicenter trial.Respiratory research · 2023Trial
- Parkinson's Disease and Respiratory Failure: Epidemiologic Insights of Two Decades From the CDC-WONDER Database.Brain and behavior · 2026Article
- Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid-Related Adverse Events Following Surgery for Breast Cancer.Clinical pharmacology and therapeutics · 2026Article
- Investigation of the Effects of Perfluorooctane Sulfonic Acid (PFOS) and Perfluorooctanoic Acid (PFOA) Exposure on Interleukin-17 Signalling and Poly(I:C)-Induced Lung Inflammation in BALB/c Mice.Basic & clinical pharmacology & toxicology · 2026Article
- Review
- Cardiac Mitochondrial Dysfunction Following Bleomycin-Induced Acute Lung Injury in Rats.bioRxiv : the preprint server for biology · 2026Article
- Trends and mortality due to acute respiratory distress syndrome in the United States (1999-2023): A 25-year nationwide study.Medicine · 2026Article
- Association between albumin-corrected anion gap and 28-day mortality in critically ill patients with pneumonia in the intensive care unit: evidence from the medical information mart for intensive care IV database.BMC pulmonary medicine · 2026Observational
- Development and validation of a machine-learning model for predicting prognosis in critically ill patients undergoing major surgery.BMC medical informatics and decision making · 2025Article
- In vitro and In Vivo Antimicrobial Activity of Melia Azedarach-Mediated Copper Oxide Nanoparticles Against Multidrug-Resistant Klebsiella pneumoniae.Current microbiology · 2025Article
- Sedation Practices during Continuous Neuromuscular Blockade for Acute Respiratory Distress Syndrome.Annals of the American Thoracic Society · 2025Article
- Artificial intelligence-driven decision support for patients with acute respiratory failure: a scoping review.Intensive care medicine experimental · 2025Review
- Association Between Albumin Corrected Anion Gap and 28-Day All-Cause Mortality in Patients With Acute Respiratory Failure in ICU: A Retrospective Study Based on the MIMIC-IV Database.The clinical respiratory journal · 2025Article
- Diaphragmatic ultrasound: approach, emerging evidence, and future perspectives in non-ICU patients.Internal and emergency medicine · 2025Review
- The impact of a multicomponent telemedicine-based intervention on quality of life in adults with respiratory failure requiring mechanical ventilation: protocol for a cluster stepped-wedge randomized clinical trial (Tele-Rehab MV Trial).Critical care science · 2025Article
- Derivation and validation of generalized sepsis-induced acute respiratory failure phenotypes among critically ill patients: a retrospective study.Critical care (London, England) · 2024Article
- Analgesia and Sedation Use During Noninvasive Ventilation for Acute Respiratory Failure.Critical care medicine · 2024Article
- Damage to the Endotracheal Tube Caused by Incessant Biting by an Unconscious Patient After Stroke: A Case Report.Cureus · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundDespite numerous advances in the understanding of the pathophysiology, progression, and management of acute respiratory failure (ARF) and ARDS, limited contemporary data are available on the mortality burden of ARF and ARDS in the United States. RESEARCH QUESTION: What are the contemporary trends and geographic variation in ARF and ARDS-related mortality in the United States? STUDY DESIGN AND
methodsA retrospective analysis of the National Center for Health Statistics' nationwide mortality data was conducted to assess the ARF and ARDS-related mortality trends from 2014 through 2018 and the geographic distribution of ARF and ARDS-related deaths in 2018 for all American residents. Piecewise linear regression was used to evaluate the trends in age-adjusted mortality rates (AAMRs) in the overall population and various demographic subgroups of age, sex, race, urbanization, and region.
resultsAmong 1,434,349 ARF-related deaths and 52,958 ARDS-related deaths during the study period, the AAMR was highest in older individuals (≥ 65 years), non-Hispanic Black people, and those living in the nonmetropolitan region. The AAMR for ARF-related deaths (per 100,000 people) increased from 74.9 (95% CI, 74.6-75.2) in 2014 to 85.6 (95% CI, 85.3-85.9) in 2018 (annual percentage change [APC], 3.4 [95% CI, 2.2-4.6]; P
interpretationThe ARF-related mortality increased at approximately 3.4% annually, and ARDS-related mortality showed a lack of decline in the last 5 years. These data contextualize important health information to guide priorities for research, clinical care, and policy, especially during the coronavirus disease 2019 pandemic in the United States.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.