Evidence map›Paper›PMID 33393054›Full record

ArticleNeuroinformatics2021

Causal Network Inference for Neural Ensemble Activity.

Rong Chen

Abstract read
In one paragraph

Article in Neuroinformatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Rong ChenDepartment of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD, 21201, USA. rong.chen.mail@gmail.com.ORCID 0000-0003-1298-9381

Funding

Dissemination of Real-time Neural Decoding for Cellular imaging LaboratoryR01NS110421 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI BHATTACHARYYA, SHUVRA S, CHEN, RONG · 2018 to 2022
$860k
NINDS NIH HHS R01 NS110421
6 · The paper itself

Abstract

Interactions among cellular components forming a mesoscopic scale brain network (microcircuit) display characteristic neural dynamics. Analysis of microcircuits provides a system-level understanding of the neurobiology of health and disease. Causal discovery aims to detect causal relationships among variables based on observational data. A key barrier in causal discovery is the high dimensionality of the variable space. A method called Causal Inference for Microcircuits (CAIM) is proposed to reconstruct causal networks from calcium imaging or electrophysiology time series. CAIM combines neural recording, Bayesian network modeling, and neuron clustering. Validation experiments based on simulated data and a real-world reaching task dataset demonstrated that CAIM accurately revealed causal relationships among neural clusters.

Indexed as

AlgorithmsBrainBayes TheoremHumansNeuronsCausal discoveryClusteringDynamic Bayesian networkNeuroimaging

Identifiers

PMID33393054
PMCPMC8233245

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.