ArticleBreast cancer (Tokyo, Japan)2021
Assessment of integrative non-pharmacological interventions and quality of life in breast cancer patients using real-world data.
Article in Breast cancer (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Randomized controlled trial on eurythmy therapy versus slow-paced physical exercises for the treatment of fatigue in metastatic breast cancer patients.The oncologist · 2025Trial
- Effect of personalized care based on OPT model on perceived control and quality of life among patients with breast cancer.Frontiers in public health · 2023Trial
- Implementing integrative nursing for oncology inpatients: a retrospective analysis of project-related routine data from 2021 to 2023.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Application of Integrative Medicine in Plastic Surgery: A Real-World Data Study.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Online eurythmy therapy for cancer-related fatigue: a prospective repeated-measures observational study exploring fatigue, stress, and mindfulness.Frontiers in integrative neuroscience · 2024Article
- Evaluation of quality of life in breast cancer patients who underwent breast-conserving surgery or mastectomy using real-world data.Breast cancer (Tokyo, Japan) · 2023Article
- Fatigue in breast cancer patients on chemotherapy: a cross-sectional study exploring clinical, biological, and genetic factors.BMC cancer · 2022Article
- Article
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundTreatments with non-pharmacological interventions (NPIs), comprising art and exercise therapies, nursing interventions, and educational components, are considered to improve quality of life of cancer patients. The aim of this study was to assess the longitudinal changes in self-reported quality of life of breast cancer patients receiving an integrative medicine program consisting of hospital-based NPIs and standard oncological treatments.
methodsThis real-world data study was conducted using data from the Network Oncology clinical registry of the Gemeinschaftskrankenhaus Havelhöhe. Primary breast cancer patients of all tumor stages, who answered the European Organization of Research and Treatment Health-Related Quality of Life Core Questionnaire scale (EORTC QLQ-C30) at first diagnosis and 12 months later, were included. Association factors between received NPIs and longitudinal EORTC QLQ-C30-changes were analyzed with additive non-parametric regression tests, considering treatment regimens and demographic variables, using the software R.
resultsA total of 231 primary breast cancer patients were enrolled and separate regression analyses were carried out. Significant associations between the received NPIs elaborate consultations and life review, nursing compresses, music and eurythmy therapy and improvements of 8-13 points for global health, all five functional EORTC-scales, and symptoms fatigue, dyspnea, insomnia, and financial difficulties were observed.
conclusionOur findings support the beneficial impact of NPIs for breast cancer patients. Further research could be directed towards synergistic effects of multimodal applied NPIs.
trial registrationTrial registration number DRKS00013335 on 27/11/2017 retrospectively registered.
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