Evidence map›Paper›PMID 33392973›Full record

ArticleInternational journal of hematology2021

Effect of donor type on volume of blood transfusions required after allogeneic hematopoietic cell transplantation.

Saiko Kurosawa, Takuhiro Yamaguchi, Saori Nakabayashi, Moemi Kasane, Misato Tsubokura, Nao Iwashita, Yuki Minakawa, Ryuzaburo Ohtake, Kimihiko Kawamura, Yukiko Nishioka and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Saiko KurosawaDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan. skurosaw@inahp.jp.
Takuhiro YamaguchiDivision of Biostatistics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Saori NakabayashiDepartment of Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
Moemi KasaneDepartment of Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
Misato TsubokuraDepartment of Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
Nao IwashitaDepartment of Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
Yuki MinakawaDepartment of Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
Ryuzaburo OhtakeDepartment of Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
Kimihiko KawamuraDepartment of Clinical Laboratories, National Cancer Center Hospital, Tokyo, Japan.
Yukiko NishiokaDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Wataru TakedaDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Tuneaki HirakawaDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Jun AokiDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Ayumu ItoDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Takashi TanakaDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Yoshihiro InamotoDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Sung-Won KimDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Minoru KojimaDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Minoko TakanashiJapanese Red Cross Society Blood Service Headquarters, Tokyo, Japan.
Takahiro FukudaDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Tokyo National Hospital · JPJapanese Red Cross Society, Japan · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We reviewed blood product use in 729 consecutive allogeneic hematopoietic cell transplantation (allo-HCT) recipients at our center to assess the volume of red blood cells (RBCs) and platelets required after allo-HCT. The median number of bags required by day 30 was 4 for RBCs (range 0-22) and 9.5 for platelets (0-53). Multivariate analysis showed that related peripheral blood stem cell transplantation (PBSCT) required a significantly lower RBC transfusion volume by day 30 compared to unrelated bone marrow transplantation (UBMT). PBSCT from haplo-identical related donors and cord blood transplantation (CBT) required a significantly greater RBC transfusion volume. For platelet transfusion, related and unrelated PBSCT required a significantly lower volume than UBMT, and CBT a greater volume. Other factors independently associated with greater RBC transfusion volume were male sex, disease status other than complete remission, and major ABO mismatch. For platelet transfusion, these were male sex, disease status, and HCT-specific comorbidity index of 1. Although the burden of blood transfusions may not be the most important factor when choosing a donor type, our findings may provide a foundation for nationwide strategies to prepare blood products and inform aspects of national healthcare expenditures.

Indexed as

Blood TransfusionPostoperative CareTissue DonorsABO Blood-Group SystemAdolescentAdultAgedBiomarkersBlood Grouping and CrossmatchingClinical Decision-MakingDisease ManagementErythrocyte IndicesFemaleHematopoietic Stem Cell TransplantationHumansMaleABO Blood-Group SystemBiomarkersAllogeneic hematopoietic cell transplantationBlood transfusionDonorPlateletRed blood cellTransfusion independence

Identifiers

PMID33392973
OpenAlexW3118859458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.