Evidence map›Paper›PMID 33392928›Full record

ArticleMaternal and child health journal2021

Mediating Factors Between Parental Socioeconomic Status and Small for Gestational Age in Infants: Results from the Hokkaido Study on Environment and Children's Health.

Naomi Tamura, Tomoyuki Hanaoka, Kumiko Ito, Atsuko Araki, Chihiro Miyashita, Sachiko Ito, Sumitaka Kobayashi, Yoichi Ito, Hisanori Minakami, Kazutoshi Cho and 6 more

Abstract read
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In one paragraph

Article in Maternal and child health journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Naomi TamuraHokkaido University Center for Environmental and Health Sciences, Kita 12, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan.
Tomoyuki HanaokaHokkaido University Center for Environmental and Health Sciences, Kita 12, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan.
Kumiko ItoHokkaido University Center for Environmental and Health Sciences, Kita 12, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan.
Atsuko ArakiHokkaido University Center for Environmental and Health Sciences, Kita 12, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan.
Chihiro MiyashitaHokkaido University Center for Environmental and Health Sciences, Kita 12, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan.
Sachiko ItoHokkaido University Center for Environmental and Health Sciences, Kita 12, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan.
Sumitaka KobayashiHokkaido University Center for Environmental and Health Sciences, Kita 12, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan.
Yoichi ItoResearch Center for Medical and Health Data Science, The Institute of Statistical Mathematics, Tokyo, Japan.
Hisanori MinakamiDepartments of Obstetrics and Gynecology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Kazutoshi ChoDepartments of Obstetrics and Gynecology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Toshiaki EndoDepartments of Obstetrics and Gynecology, School of Medicine, Sapporo Medical University, Sapporo, Japan.
Tsuyoshi BabaDepartments of Obstetrics and Gynecology, School of Medicine, Sapporo Medical University, Sapporo, Japan.
Kazuo SengokuDepartments of Obstetrics and Gynecology, Asahikawa Medical University, Asahikawa, Japan.
Toshinobu MiyamotoDepartments of Obstetrics and Gynecology, Asahikawa Medical University, Asahikawa, Japan.
Katsuhiko OgasawaraFaculties of Health Science, Hokkaido University, Sapporo, Japan.
Reiko KishiHokkaido University Center for Environmental and Health Sciences, Kita 12, Nishi 7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan. rkishi@med.hokudai.ac.jp.
Hokkaido University · JPAsahikawa Medical University · JPSapporo Medical University · JPSapporo University · JPThe Institute of Statistical Mathematics · JP

Funding

Japan Agency for Medical Research and Development JP20gk0110039Ministry of Education, Culture, Sports, Science, and Technology; and the Japan Society for the Promotion of Science (JP) JP19H01071Ministry of Education, Culture, Sports, Science, and Technology; and the Japan Society for the Promotion of Science (JP) JP19K14169Ministry of Health, Labour and Welfare H29-Kagaku Ippan-002Ministry of Health, Labour and Welfare (JP) H26-Kagaku Ippan-002
6 · The paper itself

Abstract

objectivesPrevious studies indicated a significant association between small for gestational age (SGA) in infants and their parents' socioeconomic status (SES). Thus, this study aimed to examine if parental factors, such as maternal smoking, and the pre-pregnancy body mass index (BMI) could mediate the associations between parental SES and SGA.

methodsThe participants of this study were pregnant women who enrolled in an ongoing birth cohort study, the Hokkaido study, during the first trimester of their pregnancies. A total of 14,593 live singleton births were included in the statistical analysis, of which 1011 (6.9%) were SGA. Two structural equation models were employed to evaluate the associations between parental SES, parental characteristics, and SGA.

resultsThe effect of low SES on SGA was directly mediated by maternal pre-pregnancy BMI, smoking during the third trimester, and alcohol consumption during the first trimester in the first model, which was based the assumption of independent associations between mediating factors. In the second model, which additionally considered the mediating factors from the first model, smoking during pregnancy mediated decline in parental SES, consequently increased SGA. Moreover, an increase in pregnancy smoking status increased the prevalence of lower maternal pre-pregnancy BMI and its effect on SGA. CONCLUSIONS FOR PRACTICE: In this study, we observed the independent mediating effect of maternal pre-pregnancy BMI, smoking, and alcohol consumption during pregnancy on low SES and, consequently, SGA, with the additional mediating pathway of SES to smoking to low BMI on SGA.

Indexed as

Child HealthMediation AnalysisChildCohort StudiesFemaleGestational AgeHumansInfantInfant, NewbornInfant, Small for Gestational AgeParentsPregnancyRisk FactorsSocial ClassBirth cohort studyParental tobacco smokingSmall for gestational ageSocioeconomic statusStructure equation modeling

Identifiers

PMID33392928
OpenAlexW3119110496

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.