Evidence map›Paper›PMID 33392920›Full record

ArticleMolecular biotechnology2021

Characterization of Viral Genome Encapsidated in Adeno-associated Recombinant Vectors Produced in Yeast Saccharomyces cerevisiae.

Alvaro Galli, Ilenia Iaia, Maria Serena Milella, Filippo Cipriani, Veronica Della Latta, Mauro Giacca, Lorena Zentilin, Tiziana Cervelli

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Alvaro GalliYeast Genetics and Genomics Group, Institute of Clinical Physiology, CNR, via Moruzzi 1, 56124, Pisa, Italy.
Ilenia IaiaYeast Genetics and Genomics Group, Institute of Clinical Physiology, CNR, via Moruzzi 1, 56124, Pisa, Italy.
Maria Serena MilellaYeast Genetics and Genomics Group, Institute of Clinical Physiology, CNR, via Moruzzi 1, 56124, Pisa, Italy.
Filippo CiprianiYeast Genetics and Genomics Group, Institute of Clinical Physiology, CNR, via Moruzzi 1, 56124, Pisa, Italy.
Veronica Della LattaYeast Genetics and Genomics Group, Institute of Clinical Physiology, CNR, via Moruzzi 1, 56124, Pisa, Italy.
Mauro GiaccaSchool of Cardiovascular Medicine & Sciences, British Heart Foundation Centre of Research Excellence, King's College London, SE5 9NU London, United Kingdom.
Lorena ZentilinMolecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Tiziana CervelliYeast Genetics and Genomics Group, Institute of Clinical Physiology, CNR, via Moruzzi 1, 56124, Pisa, Italy. tizicerv@ifc.cnr.it.ORCID http://orcid.org/0000-0002-9997-1741
Istituto di Fisiologia Clinica · ITInternational Centre for Genetic Engineering and Biotechnology · ITUniversity of Trieste · IT

Funding

Fondazione Pisa 127/16
6 · The paper itself

Abstract

Adeno-associated virus (AAV) is a small, non-enveloped virus used as vector in gene therapy, mainly produced in human cells and in baculovirus systems. Intense studies on these platforms led to the production of vectors with titers between 10

Indexed as

Genome, ViralDependovirusDNA, FungalGenetic VectorsGenome, FungalSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsDNA, FungalSaccharomyces cerevisiae ProteinsAdeno-associated virusEncapsidationGene therapyrAAVSaccharomyces cerevisiaeViral genome

Identifiers

PMID33392920
OpenAlexW3120264636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.