Evidence map›Paper›PMID 33392893›Full record

ArticleDocumenta ophthalmologica. Advances in ophthalmology2021

Vision before and after scharioth macular lens implantation in patients with AMD: an electrophysiological study.

Jan Kremláček, Jana Nekolová, Markéta Středová, Jana Langrová, Jana Szanyi, Miroslav Kuba, Zuzana Kubová, František Vít, Petr Voda, Martina Veselá and 1 more

Abstract read
In one paragraph

Article in Documenta ophthalmologica. Advances in ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The intraocular implant and visual rehabilitation improve the quality of life of elderly patients with geographic atrophy secondary to age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jan KremláčekDepartment of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Simkova 870, 500 38, Prague, Hradec Kralove, Czech Republic. jan.kremlacek@lfhk.cuni.cz.ORCID http://orcid.org/0000-0001-8641-4287
Jana NekolováDepartment of Ophthalmology, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-0662-8662
Markéta StředováDepartment of Ophthalmology, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0001-7713-9025
Jana LangrováDepartment of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-3639-764X
Jana SzanyiDepartment of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-0695-1312
Miroslav KubaDepartment of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0003-2525-0463
Zuzana KubováDepartment of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-8470-3218
František VítDepartment of Pathological Physiology, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0001-9834-1273
Petr VodaDepartment of Medical Biophysics, Faculty of Medicine in Hradec Kralove, Charles University, Simkova 870, 500 38, Prague, Hradec Kralove, Czech Republic.ORCID http://orcid.org/0000-0003-2751-0062
Martina VeseláDepartment of Ophthalmology, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0001-5239-0803
Naďa JiráskováDepartment of Ophthalmology, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Charles University, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-2268-7400

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor patients with age-related macular degeneration (AMD), a special intraocular lens implantation partially compensates for the loss in the central part of the visual field. For six months, we evaluated changes in neurophysiological parameters in patients implanted with a "Scharioth macula lens" (SML; a center near high add + 10 D and peripheral plano carrier bifocal lens designed to be located between the iris and an artificial lens).

methodsFourteen patients (5 M, 9 F, 63-87 years) with dry AMD were examined prior to and at 3 days after, as well as 1, 2, and 6 months after, implantation using pattern-reversal, motion-onset, and cognitive evoked potentials, psychophysical tests evaluating distant and near visual acuity, and contrast sensitivity.

resultsNear visual acuity without an external aid was significantly better six months after implantation than before implantation (Jaeger table median (lower; upper quartile): 4 (1; 6) vs. 15 (13; 17)). Distant visual acuity was significantly altered between the pre- (0.7 (0.5; 0.8) logMAR) and last postimplantation visits (0.8 (0.7; 0.8) logMAR), which matched prolongation of the P100 peak time (147 (135; 151) ms vs. 161 (141; 166) ms) of 15 arc min pattern-reversal VEPs and N2 peak time (191.5 (186.5; 214.5) ms vs. 205 (187; 218) ms) of peripheral motion-onset VEPs.

conclusionSML implantation significantly improved near vision. We also observed a slight but significant decrease in distant and peripheral vision. The most efficient electrophysiological approach to test patients with SML was the peripheral motion-onset stimulation, which evoked repeatable and readable VEPs.

Indexed as

Lenses, IntraocularMacular DegenerationElectroretinographyHumansLens Implantation, IntraocularVisual AcuityAge-related macular degenerationMaculopathyMotion-onset VEPsOddball ERPsP3bPattern-reversal VEPsScharioth macular lens

Identifiers

PMID33392893
PMCPMC8266777

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.