Evidence map›Paper›PMID 33392818›Full record

ArticleArchives of virology2021

Porcine circovirus genotypes and their copathogens in pigs with respiratory disease in southern provinces of Vietnam.

Phat Xuan Dinh, Minh Nam Nguyen, Hien The Nguyen, Vu Hoang Tran, Quy Dinh Tran, Kim Hoang Dang, Dai Tan Vo, Hien Thanh Le, Nam Thi Thu Nguyen, Toan Tat Nguyen and 1 more

Abstract read
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In one paragraph

Article in Archives of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. First report of acute reproductive disorder due toVeterinary research forum : an international quarterly journal · 2026
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  6. Coinfection ofVeterinary world · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Phat Xuan Dinh *Biotechnology Department, Nong Lam University HCMC, Linh Trung ward, Thu Duc district, Ho Chi Minh, Vietnam.
Minh Nam NguyenSchool of Medicine, Vietnam National University Ho Chi Minh City, Linh Trung ward, Thu Duc district, Ho Chi Minh, Vietnam.
Hien The NguyenDepartment of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University HCMC, Thu Duc district, Ho Chi Minh, Vietnam.
Vu Hoang TranBoehringer Ingelheim Vietnam, 39 Le Duan Street, District 1, Ho Chi Minh, Vietnam.
Quy Dinh TranBoehringer Ingelheim Vietnam, 39 Le Duan Street, District 1, Ho Chi Minh, Vietnam.
Kim Hoang DangSanphar Vietnam Co. Ltd., 59, Xuan Thuy Street, Thao Dien Ward, District 2, Ho Chi Minh, Vietnam.
Dai Tan VoDepartment of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University HCMC, Thu Duc district, Ho Chi Minh, Vietnam.
Hien Thanh LeDepartment of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University HCMC, Thu Duc district, Ho Chi Minh, Vietnam.
Nam Thi Thu NguyenDepartment of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University HCMC, Thu Duc district, Ho Chi Minh, Vietnam.
Toan Tat NguyenDepartment of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University HCMC, Thu Duc district, Ho Chi Minh, Vietnam.
Duy Tien DoDepartment of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University HCMC, Thu Duc district, Ho Chi Minh, Vietnam. duy.dotien@hcmuaf.edu.vn.ORCID http://orcid.org/0000-0002-1825-2623
Nong Lam University Ho Chi Minh City · VNBoehringer Ingelheim (United States) · USHo Chi Minh City University of Technology and Engineering · VNVietnam National University Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to investigate the genetic diversity of porcine circovirus type 2 (PCV2) and its coinfecting pathogens in pigs with respiratory disease in Vietnam. Samples from 127 clinical cases were obtained from different southern provinces of Vietnam from January 2018 to January 2020 for PCR and sequence analysis. The infection rate of PCV2 was 78.8%, and the major pathogens found in coinfections with PCV2 were porcine reproductive and respiratory syndrome virus, Mycoplasma hyopneumoniae, and Haemophilus parasuis. Forty-three PCV2-positive clinical samples were selected for amplification and sequencing of the ORF2 region. Phylogenetic analysis of PCV2 ORF2 showed that five of the sequences belonged to PCV2b (11.6%) and 38 belonged to PCV2d (88.4%), indicating that PCV2d strains were predominant in southern provinces of Vietnam. Alignment of the predicted amino acid sequences of the PCV2 capsid protein revealed polymorphic sites in the antibody recognition regions. This study demonstrates the prevalence of the PCV2d genotype in southern Vietnam and presents a comprehensive overview of the coinfecting pathogens associated with PCV2 in young pigs with respiratory disease.

Indexed as

Amino Acid SequenceAnimalsCapsid ProteinsCircoviridae InfectionsCircovirusCoinfectionGenotypePrevalenceRespiratory Tract DiseasesSwineSwine DiseasesVietnamCapsid Proteins

Identifiers

PMID33392818
OpenAlexW3119082003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.