ArticleInternational archives of occupational and environmental health2021
Exposure to bisphenol A and breast cancer risk in northern Mexican women.
Article in International archives of occupational and environmental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between ultra-processed food consumption and risk of breast cancer: a systematic review and dose-response meta-analysis of observational studies.Frontiers in nutrition · 2023Pooled it
- Bisphenol A and cancer: a critical review of the epidemiologic literature with an emphasis on exposure assessment.Environmental health : a global access science source · 2026Review
- Bisphenol A and breast cancer: Can mechanistic plausibility be reconciled with epidemiological inconsistency?iScience · 2026Review
- Associations between phenol and paraben exposure and the risk of developing breast cancer in adult women: a cross-sectional study.Scientific reports · 2025Article
- Bisphenol A and DDT disrupt adipocyte function in the mammary gland: implications for breast cancer risk and progression.Frontiers in oncology · 2025Review
- Latin America and the Caribbean Code Against cancer 1st edition: Environment, occupation, and cancer.Cancer epidemiology · 2023Article
- Protective effects of polyphenols against endocrine disrupting chemicals.Food science and biotechnology · 2022Review
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo evaluate the association between BC and urinary concentrations of free-bisphenol A (BPA-F), the biological form of BPA, among women residing in Northern Mexico.
methodsThe population under study comprised 394 histologically confirmed BC cases and 404 age-matched controls. Women were interviewed face to face about their sociodemographic and reproductive characteristics. BPA-F was determined by high-pressure liquid chromatography equipped with a fluorescence detector (HPLC/FLD). Logistic regression models were used to estimate the adjusted BC risk in relation to BPA-F.
resultsBPA-F geometric mean was significantly higher among cases compared to controls (3.16 μg/L in cases and 2.47 μg/L in controls). A significant adjusted BC odds ratio of 2.31 (95% CI: 1.43-3.74) was estimated for the highest category of BPA-F compared to the lowest category.
conclusionBPA-F may be an environmental cofactor of BC. Since this is the first report on BPA-F association with BC, our results need to be replicated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.