Evidence map›Paper›PMID 33392724›Full record

ArticleEuropean child & adolescent psychiatry2022

Testing the evolutionary advantage theory of attention-deficit/hyperactivity disorder traits.

Trine Wigh Arildskov, Anne Virring, Per Hove Thomsen, Søren D Østergaard

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Article in European child & adolescent psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Trine Wigh ArildskovDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Aarhus N, Denmark. trine.wigh.arildskov@ps.rm.dk.ORCID http://orcid.org/0000-0001-8257-8823
Anne VirringDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Aarhus N, Denmark.
Per Hove ThomsenDepartment of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Aarhus N, Denmark.
Søren D ØstergaardDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Funding

Fonden til Lægevidenskabens Fremme 15-15Hartmann Fonden R69-A28284-B23205Lundbeckfonden R208-2015-3329Novo Nordisk Fonden NNF15OC0017706The Research Foundation for Center for Child and Adolescent Psychiatry, Central Denmark Region BUC16-TWA; BUC17-TWA
6 · The paper itself

Abstract

To reconcile the strong secular persistence of attention-deficit/hyperactivity disorder (ADHD) despite its impairing effects, ADHD traits have been postulated to offer an evolutionary advantage. It has been proposed that such advantages should in particular be observable under time-critical, novel, and resource-depleted conditions requiring response-readiness and high levels of scanning and exploration/foraging. Our objective was to provide the first behavioral test of this hypothesis. Schoolchildren from the general population with no/few (n = 56), mild (n = 50), moderate (n = 48), and severe (n = 48) ADHD traits, defined according to their ADHD-Rating Scale IV (ADHD-RS-IV) total score, participated in an exploratory foraging and response-readiness laboratory test. Here, children searched for coins hidden in locations of varying obscurity in an unfamiliar room for 1 min. Test-performance (number of coins found) adjusted for age, sex, and estimated IQ was analyzed categorically using multiple linear regression analyses and dimensionally by fitting a regression model including the ADHD-RS-IV score as a continuous measure. There were no differences in the mean number of coins between the No/Few (Mean = 7.82), Mild (Mean = 7.76), Moderate (Mean = 7.58), and Severe (Mean = 7.88) groups [F(3,195) = 0.24, p = 0.871]. Furthermore, excluding children with functional impairment, adjusting for verbal working memory and response inhibition, and stratifying for sex did not change these findings. Finally, continuous ADHD traits were not found to be related to test-performance [F(3,195) = 0.73, p = 0.536]. While our results do generally not support the evolutionary advantage theory (i.e., ADHD traits neither conferred an advantage nor a disadvantage), this does not disprove that ADHD traits may have offered advantages via other mechanisms.

Indexed as

Attention Deficit Disorder with HyperactivityCentral Nervous System StimulantsChildHumansPhenotypeCentral Nervous System StimulantsAdaptive advantagesADHDChildrenDimensionalityNatural selection-based theories of ADHD

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.