Evidence map›Paper›PMID 33392644›Full record

ArticleHeart and vessels2021

Disruption of asparagine-linked glycosylation to rescue and alter gating of the Na

Pu Wang, Xiufang Zhu, Mengyan Wei, Yangong Liu, Kenshi Yoshimura, Mingqi Zheng, Gang Liu, Shinichiro Kume, Tatsuki Kurokawa, Katsushige Ono

Abstract read
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Pu Wang *Department of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Xiufang Zhu *Department of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Mengyan Wei *Department of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Yangong LiuDepartment of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Kenshi YoshimuraDepartment of Pathophysiology, Oita University School of Medicine, Yufu, Oita, 879-5593, Japan.
Mingqi ZhengDepartment of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Gang LiuDepartment of Cardiology, The First Hospital of Hebei Medical University, 89 Donggang Road, Shijiazhuang, Hebei Province, 050031, People's Republic of China.
Shinichiro KumeDepartment of Pathophysiology, Oita University School of Medicine, Yufu, Oita, 879-5593, Japan.
Tatsuki KurokawaDepartment of Pathophysiology, Oita University School of Medicine, Yufu, Oita, 879-5593, Japan.
Katsushige OnoDepartment of Pathophysiology, Oita University School of Medicine, Yufu, Oita, 879-5593, Japan. ono@oita-u.ac.jp.ORCID http://orcid.org/0000-0001-7949-1823
Hebei Medical University · CNOita University · JP

Funding

Japan Society for the Promotion of Science 25460292
6 · The paper itself

Abstract

SCN5A gene encodes the voltage-gated sodium channel Na

Indexed as

AnimalsAnimals, NewbornAsparagineCells, CulturedGlycosylationHumansMembrane PotentialsModels, AnimalMyocytes, CardiacNAV1.5 Voltage-Gated Sodium ChannelPatch-Clamp TechniquesRatsRats, WistarAsparagineNAV1.5 Voltage-Gated Sodium ChannelGlycosylationMG132NaV1.5 channelTunicamycinUbiquitin–proteasome pathway

Identifiers

PMID33392644
OpenAlexW3118929909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.