Evidence map›Paper›PMID 33392637›Full record

ArticleJournal of neurology2021

Social support is linked to mental health, quality of life, and motor function in multiple sclerosis.

Anne Kever, Korhan Buyukturkoglu, Claire S Riley, Philip L De Jager, Victoria M Leavitt

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Differential Associations Between Perceived Social Support and Cognition in Older Adults With and Without Multiple Sclerosis.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026
    Article
  5. Subjective Cognitive Complaints in Mild Traumatic Brain Injury: Association with Cognitive Test Performance and Protective Psychological Factors.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anne KeverTranslational Cognitive Neuroscience Laboratory, Department of Neurology, Columbia University Irving Medical Center, 630 W. 168th Street, New York, NY, 10032, USA.
Korhan BuyukturkogluTranslational Cognitive Neuroscience Laboratory, Department of Neurology, Columbia University Irving Medical Center, 630 W. 168th Street, New York, NY, 10032, USA.
Claire S RileyMultiple Sclerosis Center, Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
Philip L De JagerMultiple Sclerosis Center, Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA.
Victoria M LeavittTranslational Cognitive Neuroscience Laboratory, Department of Neurology, Columbia University Irving Medical Center, 630 W. 168th Street, New York, NY, 10032, USA. vl2337@cumc.columbia.edu.ORCID http://orcid.org/0000-0001-8937-6079
Columbia University Irving Medical Center · US

Funding

Reserve against Disability in Early Multiple Sclerosis (RADIEMS) Longitudinal Cohort StudyR01HD082176 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SUMOWSKI, JAMES FRANCIS · 2016 to 2025
$6.6M
National Center for Medical Rehabilitation Research of the National Institute of Child Health and Development R01 HD082176)National Multiple Sclerosis Society MB-1605-08706National Multiple Sclerosis Society RG-1508- 05892
6 · The paper itself

Abstract

objectiveTo investigate associations of social support to psychological well-being, cognition, and motor functioning in patients with multiple sclerosis (MS). Secondarily, we were interested in exploring sex differences in these relationships, based on a bioevolutionary theoretical justification.

methodsSocial support was assessed in 185 recently diagnosed patients (RADIEMS cohort), and in an independent validation sample (MEMCONNECT cohort, n = 62). Patients also completed a comprehensive neurobehavioral evaluation including measures of mental health, fatigue, quality of life, cognition, and motor function. Correlations tested links between social support and these variables, along with potential gender differences.

resultsIn both samples, higher social support was associated with better mental health, quality of life, subjective cognitive function, and less fatigue. In the RADIEMS cohort, higher social support was associated with better motor functions, particularly grip strength and gait endurance in women.

conclusionsThese findings highlight associations of social support to overall psychological health and motor functioning in persons with MS, underlining the potential opportunity of evaluating and promoting social engagement in novel treatment strategies.

Indexed as

Multiple SclerosisQuality of LifeFatigueFemaleHumansMaleMental HealthSocial Support

Identifiers

PMID33392637
OpenAlexW3119837094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.