Evidence map›Paper›PMID 33392616›Full record

Trial reportJournal of radiation research2021

A dummy-run evaluation of postoperative hypofractionated intensity-modulated radiation therapy (POHIM-RT) trials for cervical cancer.

Won Kyung Cho, Heejung Kim, Won Park, Sang-Won Kim, Jongwon Kim, Kang Kyu Lee, Jeong Geun Oh, Mee Sun Yoon, Ju-Young Song, Ki Jung Ahn and 3 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Journal of radiation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Won Kyung ChoDepartment of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Heejung KimDepartment of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Won ParkDepartment of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Sang-Won KimDepartment of Radiation Oncology, Konyang University College of Medicine, Daejeon, Republic of Korea.
Jongwon KimDepartment of Radiation Oncology, Konyang University College of Medicine, Daejeon, Republic of Korea.
Kang Kyu LeeDepartment of Radiation Oncology, Wonkwang University School of Medicine, Iksan, Republic of Korea.
Jeong Geun OhDepartment of Radiation Oncology, Wonkwang University School of Medicine, Iksan, Republic of Korea.
Mee Sun YoonDepartment of Radiation Oncology, Chonnam National University Medical School, Gwangju, Republic of Korea.
Ju-Young SongDepartment of Radiation Oncology, Chonnam National University Medical School, Gwangju, Republic of Korea.
Ki Jung AhnDepartment of Radiation Oncology, Inje University Busan Paik Hospital, Busan, Republic of Korea.
Sung Kwang ParkDepartment of Radiation Oncology, Inje University Busan Paik Hospital, Busan, Republic of Korea.
Jin Hwa ChoiDepartment of Radiation Oncology, Chung-Ang University Hospital, Seoul, South Korea.
Jino BakDepartment of Radiation Oncology, Chung-Ang University Hospital, Seoul, South Korea.
Chonnam National University Hospital · KRChung-Ang University Hospital · KRInje University Busan Paik Hospital · KRKonyang University · KRSamsung Medical Center · KRWonkwang University · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The postoperative hypofractionated intensity-modulated radiation therapy (POHIM-RT) trial is a phase II study to evaluate toxicity following hypofractionated intensity modulated radiation therapy (IMRT) for cervical cancer. This study describes the results of a benchmark procedure for RT quality assurance of the POHIM-RT trial. Six participating institutions were provided computed tomography for RT planning and an IMRT plan for a sample and were instructed to delineate volumes, create a treatment plan and quality assurance (QA) plan, and submit the results of all procedures. The inter-institutional agreements on RT volume and plan results were evaluated using the kappa value and dice similarity coefficients. The simultaneous truth and performance level estimation (STAPLE) method was employed to generate a consensus target volume. The treatment volumes, organs-at-risk volumes, and results of the RT plan and QA reported by the institutions were acceptable and adhered well to the protocol. In terms of clinical target volume (CTV) delineation, there were differences between the institutions, particularly in vaginal cuff and paracolpium subsites. Consensus CTV was generated from the collected CTVs with the STAPLE method. The participating institutions showed considerable agreement regarding volume, dose and QA results. To improve CTV agreement in CTV, we provided feedback with images of the consensus target volume and detailed written guidelines for specific subsites that were the most heterogeneous.

Indexed as

Radiation Dose HypofractionationRadiotherapy, Intensity-ModulatedFemaleHumansOrgans at RiskPostoperative PeriodQuality Assurance, Health CareRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedUterine Cervical Neoplasmscervical cancerhypofractionationIMRT

Identifiers

PMID33392616
PMCPMC7779361
OpenAlexW3118306465

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.