Evidence map›Paper›PMID 33392514›Full record

ArticleBlood cancer discovery2020

PRPS-ST: A protocol-agnostic self-training method for gene expression-based classification of blood cancers.

Aixiang Jiang, Laura K Hilton, Jeffrey Tang, Christopher K Rushton, Bruno M Grande, David W Scott, Ryan D Morin

Open access · greenAbstract read
In one paragraph

Article in Blood cancer discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Aixiang Jiang *Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-6153-7595
Laura K Hilton *BC Cancer Centre for Lymphoid Cancer, Vancouver, British Columbia, Canada.ORCID 0000-0002-6413-6586
Jeffrey TangDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.ORCID 0000-0002-5633-6123
Christopher K RushtonDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada.ORCID 0000-0001-6306-9361
Bruno M GrandeBC Cancer Centre for Lymphoid Cancer, Vancouver, British Columbia, Canada.ORCID 0000-0002-4621-1589
David W ScottBC Cancer Centre for Lymphoid Cancer, Vancouver, British Columbia, Canada.
Ryan D MorinDepartment of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada. rdmorin@sfu.ca.
Simon Fraser University · CAUniversity of British Columbia · CASpinal Cord Injury BC · CA

Funding

Preclinical Models and Therapeutics CoreP01CA229100 · NCI · MAYO CLINIC ARIZONA · PI SCOTT, DAVID WILLIAM · 2018 to 2022
$10.2M
NCI NIH HHS P01 CA229100
6 · The paper itself

Abstract

Gene expression classifiers are gaining increasing popularity for stratifying tumors into subgroups with distinct biological features. A fundamental limitation shared by current classifiers is the requirement for comparable training and testing data sets. Here, we describe a self-training implementation of our

Indexed as

Hematologic NeoplasmsNeoplasmsGene ExpressionHumansB-ALLbinary classifierhematologicmachine learningmolecular subgroup

Identifiers

PMID33392514
PMCPMC7774870
OpenAlexW3086857979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.