Evidence map›Paper›PMID 33392511›Full record

ArticleAnaesthesia reports

Emergency biventricular assist device implantation in a patient with suspected COVID-19 disease.

N Nwaejike, T Strang, M Garcia, M Charlesworth, S M Shaw, J B Barnard

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Anaesthesia reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

N NwaejikeDepartment of Cardiothoracic Surgery Wythenshawe Hospital Manchester University Foundation Trust Manchester UK.
T StrangDepartment of Cardiothoracic Anaesthesia Critical Care and ECMO Wythenshawe Hospital Manchester University Foundation Trust Manchester UK.
M GarciaDepartment of Cardiothoracic Anaesthesia Critical Care and ECMO Wythenshawe Hospital Manchester University Foundation Trust Manchester UK.
M CharlesworthDepartment of Cardiothoracic Anaesthesia Critical Care and ECMO Wythenshawe Hospital Manchester University Foundation Trust Manchester UK.
S M ShawDepartment of Cardiology Wythenshawe Hospital Manchester University Foundation Trust Manchester UK.
J B BarnardDepartment of Cardiothoracic Surgery Wythenshawe Hospital Manchester University Foundation Trust Manchester UK.
Wythenshawe Hospital · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe coronavirus disease 2019 (COVID-19) is a multisystem inflammatory disorder and knowledge and experience with severe acute respiratory failure in infected patients has grown considerably since reports of the first few cases. Little is known about the effect of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) virus on the heart, and it has been suggested that fulminant cardiac failure, with or without respiratory failure, may occur several weeks following infection. A young man presented after a recent viral illness. He was in severe cardiogenic shock and was implanted with an emergency biventricular assist device, which also incorporated an extracorporeal membrane oxygenator. He stabilised soon after and, despite an intracerebral haemorrhage which resolved and bleeding into the trachea following percutaneous tracheostomy, he survived to explant and was successfully stepped down to a rehabilitation unit on postoperative day 50. He tested positive for SARS-CoV-2 antibodies when the test became available on postoperative day 33. We envisage there will be many more such presentations of acute COVID-19-associated cardiogenic shock and we recommend clinicians consider this diagnosis when presented with an acutely unwell patient with an unclear diagnosis following a viral illness. These patients should be discussed as early as possible with a transplant/mechanical circulatory support team.

Indexed as

biventricular assist deviceCOVID‐19extracorporeal membrane oxygenationmechanical circulatory support

Identifiers

PMID33392511
PMCPMC7772647
OpenAlexW3111174022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.