Evidence map›Paper›PMID 33392374›Full record

ArticleOne health (Amsterdam, Netherlands)2020

Farm animal contact is associated with progression to Hemolytic uremic syndrome in patients with Shiga toxin-producing

Madhura S Vachon, Myda Khalid, Gillian A M Tarr, Craig Hedberg, Jennifer A Brown

Open access · goldAbstract read
In one paragraph

Article in One health (Amsterdam, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Epidemiological Characterization of Isolates ofAnimals : an open access journal from MDPI · 2023
    Article
  4. Risk Factors for Positivity to Shiga Toxin-ProducingInternational journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Madhura S VachonDivision of Environmental Health Sciences, University of Minnesota School of Public Health, 420 Delaware St. SE, Minneapolis, MN, USA, 55455.
Myda KhalidDepartment of Pediatric Nephrology and Kidney Diseases, Riley Hospital for Children 575 Riley Hospital Dr., Indianapolis, IN, USA, 46202.
Gillian A M TarrDivision of Environmental Health Sciences, University of Minnesota School of Public Health, 420 Delaware St. SE, Minneapolis, MN, USA, 55455.
Craig HedbergDivision of Environmental Health Sciences, University of Minnesota School of Public Health, 420 Delaware St. SE, Minneapolis, MN, USA, 55455.
Jennifer A BrownEpidemiology Resource Center, Indiana State Department of Health, 2 N. Meridian St. Indianapolis, IN, USA, 46204.
Minnesota Department of Health · USIndiana State Department of Health · USRiley Hospital for Children · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemolytic uremic syndrome (HUS) is a life-threatening complication of Shiga toxin-producing

methodsExposure data for laboratory-confirmed STEC cases among Indiana residents during 2012-2018 were retrieved. Logistic regression and mediation analysis were performed to determine the extent to which a history of direct contact with farm animals was associated with post-diarrheal HUS independent of age and mediated by

resultsA total of 784 STEC cases were retrieved. Of these, 46 (6%) developed HUS. Complete exposure data were available for 600 (77%) cases. A total of 24 (52%) HUS patients reported direct contact with farm animals, while 114 (21%) STEC patients who did not develop HUS reported this exposure. Among all STEC cases, HUS was associated with direct farm animal contact after adjusting for age (OR = 3.40, 95% CI: 1.81, 6.40). Detection of

conclusionsDirect farm animal contact was a risk factor for development of HUS among laboratory-confirmed STEC cases, independent of

Indexed as

Farm animalHemolytic uremic syndromeMediationShiga toxin-producing E. colistx2

Identifiers

PMID33392374
PMCPMC7772627
OpenAlexW3089801444

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.