Evidence map›Paper›PMID 33392197›Full record

ArticleFrontiers in cell and developmental biology2020

Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma.

Juan Du, Zhen Dong, Li Tan, Mengqin Tan, Fang Zhang, Kui Zhang, Guangzhao Pan, Chongyang Li, Shaomin Shi, Yanli Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Cell Death Modalities in Therapy of Melanoma.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Frontiers in pharmacology · 2022
    Article
  16. Chinese endemic medicinal plantFrontiers in pharmacology · 2022
    Review
  17. Article
  18. Review
  19. The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment.Evidence-based complementary and alternative medicine : eCAM · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Juan DuDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Zhen DongState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture and Textile and Biomass, Chongqing, China.
Li TanState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture and Textile and Biomass, Chongqing, China.
Mengqin TanState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture and Textile and Biomass, Chongqing, China.
Fang ZhangDepartment of Nuclear Medicine, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Kui ZhangState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture and Textile and Biomass, Chongqing, China.
Guangzhao PanState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture and Textile and Biomass, Chongqing, China.
Chongyang LiState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture and Textile and Biomass, Chongqing, China.
Shaomin ShiDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Yanli ZhangDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Yaling LiuDepartment of Dermatology, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Hongjuan CuiState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture and Textile and Biomass, Chongqing, China.
Southwest University · CNState Key Laboratory of Silkworm Genomic BiologyThird Hospital of Hebei Medical University · CNSericultural Research Institute · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tubeimoside I (TBMS1), also referred to as tubeimoside A, is a natural compound extracted from the plant Tu Bei Mu (

Indexed as

autophagyMEK1/2-ERK1/2 cascademelanomaPTP1Btubeimoside-1

Identifiers

PMID33392197
PMCPMC7773826
OpenAlexW3111963866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.