Evidence map›Paper›PMID 33392093›Full record

ArticleFrontiers in oncology2020

Dosimetric Feasibility Study of Dose Escalated Stereotactic Body Radiation Therapy (SBRT) in Locally Advanced Pancreatic Cancer (LAPC) Patients: It Is Time to Raise the Bar.

Renzo Mazzarotto, Nicola Simoni, Stefania Guariglia, Gabriella Rossi, Renato Micera, Riccardo De Robertis, Alessio Pierelli, Emanuele Zivelonghi, Giuseppe Malleo, Salvatore Paiella and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Renzo MazzarottoDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Nicola SimoniDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Stefania GuarigliaDepartment of Medical Physics, University of Verona Hospital Trust, Verona, Italy.
Gabriella RossiDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Renato MiceraDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Riccardo De RobertisDepartment of Radiology, University of Verona Hospital Trust, Verona, Italy.
Alessio PierelliDepartment of Medical Physics, University of Verona Hospital Trust, Verona, Italy.
Emanuele ZivelonghiDepartment of Medical Physics, University of Verona Hospital Trust, Verona, Italy.
Giuseppe MalleoDepartment of General and Pancreatic Surgery, University of Verona Hospital Trust, Verona, Italy.
Salvatore PaiellaDepartment of General and Pancreatic Surgery, University of Verona Hospital Trust, Verona, Italy.
Roberto SalviaDepartment of General and Pancreatic Surgery, University of Verona Hospital Trust, Verona, Italy.
Carlo CavedonDepartment of Medical Physics, University of Verona Hospital Trust, Verona, Italy.
Michele MilellaDepartment of Oncology, University of Verona Hospital Trust, Verona, Italy.
Claudio BassiDepartment of General and Pancreatic Surgery, University of Verona Hospital Trust, Verona, Italy.
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveTo assess the dosimetric feasibility of a stereotactic body radiotherapy (SBRT) dose escalated protocol, with a simultaneous integrated boost (SIB) and a simultaneous integrated protection (SIP) approach, in patients with locally advanced pancreatic cancer (LAPC). MATERIAL AND

methodsTwenty LAPC lesions, previously treated with SBRT at our Institution, were re-planned. The original prescribed and administered dose was 50/30/25 Gy in five fractions to PTV

resultsPTV

conclusionsIn LAPC patients SBRT, with a SIB/SIP dose escalation approach up to 60/40/33 Gy in five fractions to PTV

Indexed as

ablative dosedose escalationlocally advancedpancreatic cancerstereotactic body radiotherapy

Identifiers

PMID33392093
PMCPMC7773844
OpenAlexW3110843904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.