Evidence map›Paper›PMID 33392071›Full record

ArticleFrontiers in oncology2020

Prognostic and Predictive Value of the American Joint Committee on Cancer Pathological Prognostic Staging System in Nodal Micrometastatic Breast Cancer.

Jian Shi, Chen-Lu Lian, Feng Chi, Ping Zhou, Jian Lei, Li Hua, Jun Wang, Zhen-Yu He, San-Gang Wu

Abstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jian ShiDivision of Breast Surgery, the University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Chen-Lu LianDepartment of Radiation Oncology, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Feng ChiDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.
Ping ZhouDepartment of Radiation Oncology, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Jian LeiDepartment of Obstetrics and Gynecology, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Li HuaDepartment of Obstetrics and Gynecology, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Jun WangDepartment of Radiation Oncology, the First Affiliated Hospital of Xiamen University, Xiamen, China.
Zhen-Yu HeDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou, China.
San-Gang WuDepartment of Radiation Oncology, the First Affiliated Hospital of Xiamen University, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo investigate the prognostic and predictive effect of the American Joint Committee on Cancer (AJCC) 8

methodsData from T1-2N1micM0 breast cancer patients who underwent mastectomy from 2010-2014 were obtained from the Surveillance, Epidemiology, and End Results program. The chi-square test, binomial logistics regression, receiver-operating characteristics curve, competing-risk regression model, Cox proportional hazards regression model, and proportional hazard assumption were used for statistical analyses.

resultsWe identified 4,729 patients, including 1,062 patients were received postmastectomy radiotherapy (PMRT). Stage change occurred in 88.2% of the patients, of which 84.4% were downstaged and 3.7% were upstaged. Patients with higher pathological prognostic stages were independently predicted to receive PMRT. The 5-year breast cancer-specific survival (BCSS) was 97.5, 93.7, 90.1, 86.0, and 73.5% in disease stages IA, IB, IIA, IIB, and IIIA, respectively, according to the 8

conclusionsThe 8

Indexed as

AJCC stagingbreast cancermastectomynodal micrometastasisradiotherapy

Identifiers

PMID33392071
PMCPMC7775531

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.