Evidence map›Paper›PMID 33392050›Full record

ArticleAfrican journal of laboratory medicine2020

Haematological indices of sickle cell patients with chronic leg ulcers on compression therapy.

Oluwatoyin A Babalola, Ayodele Ogunkeyede, Abayomi B Odetunde, Foluke Fasola, Anthony A Oni, Chinedum P Babalola, Adeyinka G Falusi

Open access · diamondAbstract read
In one paragraph

Article in African journal of laboratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Oluwatoyin A BabalolaInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID https://orcid.org/0000-0002-4979-8135
Ayodele OgunkeyedeDepartment of Surgery, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.ORCID https://orcid.org/0000-0001-7074-250X
Abayomi B OdetundeInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID https://orcid.org/0000-0001-6513-1165
Foluke FasolaDepartment of Haematology, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID https://orcid.org/0000-0002-5841-9678
Anthony A OniDepartment of Medical Microbiology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Chinedum P BabalolaInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID https://orcid.org/0000-0001-9173-8032
Adeyinka G FalusiInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID https://orcid.org/0000-0002-3064-3336
University of Ibadan · NGInstitute for Advanced Medical Research · USUniversity of Ilorin Teaching Hospital · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrent chronic leg ulcers and its are morbidities associated with sickle cell anaemia (SCA). Compression therapy increases the rate of healing of these ulcers and also decreases the rate of recurrence.

objectiveThis study evaluated the haematological parameters of patients with SCA and chronic leg ulcers placed on high compression bandaging to provide data for improved ulcer management and prevention.

methodsEighteen patients with SCA and chronic leg ulcers were recruited for treatment by compression therapy in Ibadan, Nigeria, from March to June 2015. Eighteen SCA patients with no history of chronic leg ulcers were age and sex matched and recruited as controls. Blood samples, wound biopsies and swabs were collected at different time points for full blood count, microbiology, culture and antimicrobial susceptibility tests. Haemoglobin variants were quantified by high performance liquid chromatography. Fasting blood sugar was tested for leg ulcer patients to determine diabetic status.

resultsUlcers ranged from 0.5 cm

conclusionMeasures to improve haematological parameters during leg ulcer treatment in SCA patients should be taken to aid wound healing.

Indexed as

chronic leg ulcercompression therapyhaematological parameterssickle cell anaemiawound healing

Identifiers

PMID33392050
PMCPMC7756931
OpenAlexW3113862354

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.