ArticleQuantitative imaging in medicine and surgery2021
Slice-stacking T2-weighted MRI for fast determination of internal target volume for liver tumor.
Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Novel monodisperse FePt nanocomposites for T2-weighted magnetic resonance imaging: biomedical theranostics applications.Nanoscale advances · 2022Review
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5 authors.
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Abstract
backgroundTo investigate the feasibility of generating maximum intensity projection (MIP) images to determine internal target volume (ITV) using slice-stacking MRI (SS-MRI) technique.
methodsSlice-stacking is a technique which applies a multi-slice MRI acquisition to generate a 3D MIP for ITV contouring, without reconstructing 4D-MRI. 4D digital extended cardiac-torso (XCAT) phantom was used to generate MIP images with sequential 2D HASTE sequence, with different tumor diameters (10, 30 and 50 mm) and with simulated regular and irregular (patient) breathing motions. A reference MIP was generated using all acquisition images. Consecutive repetitions were then used to generate MIP to analyze the relationship between Dice's similarity coefficient (DSC) and the number of repetitions, and the relationship between the relative ITV volume difference and the number of repetitions. Images from XCAT phantom and from three hepatic carcinoma patients were collected in this study to demonstrate the feasibility of this technique.
resultsFor both regular and irregular breathing motion, the average DSC of ITV is >0.94 and the average relative ITV volume difference is <10% (approximately 0.15 cm
conclusionsThe number of scans required to generate tumor ITV for slice-stacking method (5-7 repetition) is 3-4 times less than that of 4D-MRI (15-20 repetitions). It is feasible to generate a fast clinically acceptable ITV using slice-stacking method with sequential 2D MR images.
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