Evidence map›Paper›PMID 33391995›Full record

ArticleToxicology reports2021

4-Methylcyclohexane methanol (MCHM) affects viability, development, and movement of

Mark Perfetto, Scotia G Kirkham, Michael C Ayers, Shuo Wei, Jennifer E G Gallagher

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mark PerfettoDepartment of Biology, 53 Campus Drive, University of West Virginia, Morgantown, WV, 26506, USA.
Scotia G KirkhamDepartment of Biology, 53 Campus Drive, University of West Virginia, Morgantown, WV, 26506, USA.
Michael C AyersDepartment of Biology, 53 Campus Drive, University of West Virginia, Morgantown, WV, 26506, USA.
Shuo WeiDepartment of Biology, 53 Campus Drive, University of West Virginia, Morgantown, WV, 26506, USA.
Jennifer E G GallagherDepartment of Biology, 53 Campus Drive, University of West Virginia, Morgantown, WV, 26506, USA.
West Virginia University · US

Funding

A conserved ADAM-ephrin-Wnt signaling axis in neural crest development and cancerR01GM114105 · NIGMS · WEST VIRGINIA UNIVERSITY · PI WEI, SHUO · 2015 to 2019
$1.5M
A Systems Approach to Understanding Effects of MCHM on Cellular MetabolismR15ES026811 · NIEHS · WEST VIRGINIA UNIVERSITY · PI GALLAGHER, JENNIFER · 2016 to 2016
$448k
NIEHS NIH HHS R15 ES026811NIGMS NIH HHS R01 GM114105
6 · The paper itself

Abstract

Following chemical spill disasters, it is important to estimate the effects of spilled chemicals on humans and the environment. Here we analyzed the toxicological effects of the coal cleaning chemical, 4-methylcyclohexane methanol (MCHM), which was spilled into the Elk River water supply in 2014. The viability of HEK293 T human cell line cultures and

Indexed as

MCHMMelanocytesNon-responsiveROSXenopus

Identifiers

PMID33391995
PMCPMC7772722
OpenAlexW3117743711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.