ReviewClinical kidney journal2020
An update review of intradialytic hypotension: concept, risk factors, clinical implications and management.
Review in Clinical kidney journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 137 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimal Frequency of Total Body Water Measurements by Bioelectrical Impedance Analysis to Prevent Intradialytic Hypotension
Randomised Controlled Trial of Dialysate Cooling for the Preservation of Cognitive Function in People Receiving Haemodialysis
Who cites it
137 citing papers in PubMed, 3 syntheses or guidelines pooled it, 208 citations in OpenAlex.
- Effectiveness of Nursing and Non-Pharmacological Interventions in Reducing Intradialytic Hypotension Among Haemodialysis Patients: A Systematic Review and Meta-Analysis.Nursing open · 2026Pooled it
- Prediction of intradialytic hypotension by machine learning: A systematic review.Journal of nephrology · 2025Pooled it
- Systematic review and meta-analysis of cardiovascular event risk prediction models in maintenance hemodialysis patients.Scientific reports · 2025Pooled it
- Short-term effect of oral glucose solution in older patients with hypoglycemia undergoing hemodialysis.Frontiers in endocrinology · 2026Trial
- The hemodynamic cost of intermittent hemodialysis and systemic organ stunning.Renal failure · 2026Review
- Tenapanor Beyond Phosphate: Gut Sodium Transport, Stool Transit Time, and Volume Balance in Dialysis Patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Review
- Intraprocedural Hemodynamics During Concomitant Rheocarna Therapy and Maintenance Hemodialysis: Effects of Dialyzer Membrane Type and Circuit Sequence.Journal of clinical apheresis · 2026Article
- Association of limb ischemic preconditioning with intradialytic hypotension in patients with diabetic kidney disease undergoing hemodialysis: a retrospective analysis.International urology and nephrology · 2026Article
- Effect of reduced ultrafiltration rate on the cardiac biomarkers NT-proBNP and troponin T: a prospective crossover study.BMC nephrology · 2026Article
- Lower- Versus Conventional-Sodium Dialysate and Left Ventricular Mass in Patients Receiving Hemodialysis: Causal Analyses of a Randomized Clinical Trial.Kidney medicine · 2026Article
- A Narrative Summary of Strategies to Mitigate Intradialytic Hypotension in Poisoned Patients Requiring Extracorporeal Toxin Elimination.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026Review
- Article
- Central Retinal Artery Occlusion Following Intradialytic Hypotension in End-Stage Renal Disease.Cureus · 2026Article
- Mechanical thromboprophylaxis for preventing intradialytic hypotension in people undergoing maintenance haemodialysis.The Cochrane database of systematic reviews · 2026Article
- Mind the Gut: Cognitive Decline, Microbiota, and Nutrition-Related Modulators in Older Adults with Chronic Kidney Disease.Nutrients · 2026Review
- Targeted strategies for managing seasonal blood pressure swings in high-risk hemodialysis patients.Journal of cardiothoracic surgery · 2026Article
- Intradialytic hypotension and hemodynamic phenotypes in children following continuous renal replacement therapy initiation.Pediatric research · 2026Observational
- The Role of Online Hemodiafiltration in Contemporary Kidney Care.Clinical journal of the American Society of Nephrology : CJASN · 2026Review
- Article
- Article
77 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intradialytic hypotension (IDH) is a frequent and serious complication of chronic haemodialysis, linked to adverse long-term outcomes including increased cardiovascular and all-cause mortality. IDH is the end result of the interaction between ultrafiltration rate (UFR), cardiac output and arteriolar tone. Thus excessive ultrafiltration may decrease the cardiac output, especially when compensatory mechanisms (heart rate, myocardial contractility, vascular tone and splanchnic flow shifts) fail to be optimally recruited. The repeated disruption of end-organ perfusion in IDH may lead to various adverse clinical outcomes affecting the heart, central nervous system, kidney and gastrointestinal system. Potential interventions to decrease the incidence or severity of IDH include optimization of the dialysis prescription (cool dialysate, UFR, sodium profiling and high-flux haemofiltration), interventions during the dialysis session (midodrine, mannitol, food intake, intradialytic exercise and intermittent pneumatic compression of the lower limbs) and interventions in the interdialysis period (lower interdialytic weight gain and blood pressure-lowering drugs). However, the evidence base for many of these interventions is thin and optimal prevention and management of IDH awaits further clinical investigation. Developing a consensus definition of IDH will facilitate clinical research. We review the most recent findings on risk factors, pathophysiology and management of IDH and, based on this, we call for a new consensus definition of IDH based on clinical outcomes and define a roadmap for IDH research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.