Evidence map›Paper›PMID 33391692›Full record

ArticleEcology and evolution2020

Coupling between tolerance and resistance for two related

Alice Balard, Víctor Hugo Jarquín-Díaz, Jenny Jost, Vivian Mittné, Francisca Böhning, Ľudovít Ďureje, Jaroslav Piálek, Emanuel Heitlinger

Abstract read
In one paragraph

Article in Ecology and evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alice BalardDepartment of Molecular Parasitology Institute for Biology Humboldt University Berlin (HU) Berlin Germany.ORCID https://orcid.org/0000-0002-0942-7479
Víctor Hugo Jarquín-DíazDepartment of Molecular Parasitology Institute for Biology Humboldt University Berlin (HU) Berlin Germany.ORCID https://orcid.org/0000-0003-3758-1091
Jenny JostDepartment of Molecular Parasitology Institute for Biology Humboldt University Berlin (HU) Berlin Germany.ORCID https://orcid.org/0000-0003-2563-1637
Vivian MittnéDepartment of Molecular Parasitology Institute for Biology Humboldt University Berlin (HU) Berlin Germany.
Francisca BöhningDepartment of Molecular Parasitology Institute for Biology Humboldt University Berlin (HU) Berlin Germany.ORCID https://orcid.org/0000-0002-7561-5005
Ľudovít ĎurejeResearch Facility Studenec Institute of Vertebrate Biology Czech Academy of Sciences Brno Czech Republic.
Jaroslav PiálekResearch Facility Studenec Institute of Vertebrate Biology Czech Academy of Sciences Brno Czech Republic.ORCID https://orcid.org/0000-0002-0829-7481
Emanuel HeitlingerDepartment of Molecular Parasitology Institute for Biology Humboldt University Berlin (HU) Berlin Germany.ORCID https://orcid.org/0000-0002-7139-3425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance (host capacity to reduce parasite burden) and tolerance (host capacity to reduce impact on its health for a given parasite burden) manifest two different lines of defense. Tolerance can be independent from resistance, traded off against it, or the two can be positively correlated because of redundancy in underlying (immune) processes. We here tested whether this coupling between tolerance and resistance could differ upon infection with closely related parasite species. We tested this in experimental infections with two parasite species of the genus

Indexed as

coevolutionEimeriaresistancetolerance

Identifiers

PMID33391692
PMCPMC7771152

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.