Evidence map›Paper›PMID 33391648›Full record

ArticleJournal of surgical case reports2020

Successful surgical treatment of a patient with primary insulinoma of the liver.

A Kriger, S Berelavichus, D Gorin, G Galkin, M Yukina, I Ilovayskaya, V Zektser, N Nuralieva, A R Kaldarov

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1 citations in OpenAlex.

  1. Primary Hepatic Neuroendocrine Neoplasms: Systematic Review and Expert Pathologist Reappraisal Using the WHO 6th Edition Framework.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Ectopic insulinoma: a systematic review.Reviews in endocrine & metabolic disorders · 2023
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

A KrigerDepartment No.1 of A.V. Vishnevsky Center of Surgery, 5 Universitetsky Prospekt 289, Moscow 119296, Russia.
S BerelavichusDepartment No.1 of A.V. Vishnevsky Center of Surgery, 16/1 Solov'iny Proezd 139, Moscow 117593, Russia.
D GorinDepartment No.1 of A.V. Vishnevsky Center of Surgery, 40 Seslavinskaya Street 48, Moscow 121309, Russia.
G GalkinDepartment No.1 of A.V. Vishnevsky Center of Surgery, 37/21 Tuhachevskogo Street 131, Moscow 123159, Russia.
M YukinaDepartment of National Medical Research Centre of Endocrinology, 11, Dm Ulyanova, Moscow 117036, Russia.
I IlovayskayaMoscow Regional Research & Clinical Institute (MONIKI), 61/2 Schepkina Street, Moscow 129110, Russia.
V ZektserI.M. Sechenov First Medical State University, 8/2 Trubetskaya street, Moscow 119991, Russia.
N NuralievaDepartment of National Medical Research Centre of Endocrinology 11, Dm Ulyanova, Moscow 117036, Russia.
A R KaldarovDepartment No.1 of A.V. Vishnevsky Center of Surgery, 9, Novoe Shosse 78, Drojjino, Moscow 142718, Russia.ORCID 0000-0002-4486-4594
National Medical Research Center of Surgery named after A. Vishnevsky · RUMoscow Regional Scientific Research Clinical Institute. MF Vladimirsky · RUSechenov University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulinoma is the most frequent functional neuroendocrine tumor of the pancreas, which causes organic hyperinsulinism with severe hypoglycemia. There are no cases of primary insulinoma of the liver described. A 63-year-old female was admitted to our center presenting symptoms of severe hypoglycemia due to confirmed endogenic hyperinsulinism. None of the performed diagnostic procedures could reveal a pancreatic tumor. However, a pathologic mass in the sixth segment of the liver was detected. We performed arterial calcium stimulation that showed increased levels of insulin and c-peptide in almost all stimulated arteries. The highest and most prolonged peaks were detected at the points of the common hepatic artery and the right hepatic artery. After the surgical removal of the liver tumor, the blood glucose level was stabilized within the normal range. Post-operative pathomorphological investigation confirmed the diagnosis of a neuroendocrine tumor. The long-term survival results show correct treatment tactics without any signs of disease recurrence.

Indexed as

insulinomaliverneuroendocrine neoplasmneuroendocrine tumor

Identifiers

PMID33391648
PMCPMC7769218
OpenAlexW3113566694

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.