Evidence map›Paper›PMID 33391535›Full record

ArticleTheranostics2021

Blocking NHE1 stimulates glioma tumor immunity by restoring OXPHOS function of myeloid cells.

Md Nabiul Hasan, Lanxin Luo, Dawei Ding, Shanshan Song, Mohammad Iqbal H Bhuiyan, Ruijia Liu, Lesley M Foley, Xiudong Guan, Gary Kohanbash, T Kevin Hitchens and 3 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 49 citations in OpenAlex.

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  17. Acid-base transporters in the context of tumor heterogeneity.Pflugers Archiv : European journal of physiology · 2024
    Review
  18. Article
  19. Article
  20. Ion Channels in Gliomas-From Molecular Basis to Treatment.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Md Nabiul HasanDepartment of Neurology and Pittsburgh Institute for Neurodegenerative Disease, University of Pittsburgh, Pittsburgh, PA 15213.
Lanxin LuoDepartment of Neurology and Pittsburgh Institute for Neurodegenerative Disease, University of Pittsburgh, Pittsburgh, PA 15213.
Dawei DingDepartment of Neurology and Pittsburgh Institute for Neurodegenerative Disease, University of Pittsburgh, Pittsburgh, PA 15213.
Shanshan SongDepartment of Neurology and Pittsburgh Institute for Neurodegenerative Disease, University of Pittsburgh, Pittsburgh, PA 15213.
Mohammad Iqbal H BhuiyanDepartment of Neurology and Pittsburgh Institute for Neurodegenerative Disease, University of Pittsburgh, Pittsburgh, PA 15213.
Ruijia LiuDepartment of Neurology and Pittsburgh Institute for Neurodegenerative Disease, University of Pittsburgh, Pittsburgh, PA 15213.
Lesley M FoleyAnimal Imaging Center, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213.
Xiudong GuanDepartment of Neurology and Pittsburgh Institute for Neurodegenerative Disease, University of Pittsburgh, Pittsburgh, PA 15213.
Gary KohanbashDepartment of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213.
T Kevin HitchensAnimal Imaging Center, University of Pittsburgh, Pittsburgh, Pennsylvania, 15213.
Maria G CastroDepartment of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI, USA.
Zhongling ZhangDepartment of Neurology, First Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.
Dandan SunDepartment of Neurology and Pittsburgh Institute for Neurodegenerative Disease, University of Pittsburgh, Pittsburgh, PA 15213.
University of Pittsburgh · USImaging Center · USUniversity of Michigan–Ann Arbor · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0M
NCI NIH HHS P30 CA047904
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBrain NeoplasmsCell Line, TumorDisease Models, AnimalFemaleGliomaGlucoseImmune ToleranceImmunotherapyMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMicrogliaMitochondriaGlucoseSlc9a1 protein, mouseSodium-Hydrogen Exchanger 1Temozolomideanti-PD-1 therapyglycolysisimmunosuppressiontemozolomidetumor-associated microglia/macrophage

Identifiers

PMID33391535
PMCPMC7738877
OpenAlexW3112213465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.