Evidence map›Paper›PMID 33391503›Full record

ArticleTheranostics2021

Metabolomic profiling reveals amino acid and carnitine alterations as metabolic signatures in psoriasis.

Chao Chen, Guixue Hou, Chunwei Zeng, Yan Ren, Xiang Chen, Cong Peng

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chao ChenDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Guixue HouBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Chunwei ZengBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Yan RenBGI-Shenzhen, Shenzhen, Guangdong, 518083, China.
Xiang ChenDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Cong PengDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
BGI Group (China) · CNCentral South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput metabolite profiling provides the opportunity to reveal metabolic mechanisms and identify biomarkers. Psoriasis is an immune-mediated chronic inflammatory disease. However, the role of metabolism in psoriasis pathogenesis remains unclear.

Indexed as

Disease Models, AnimalMetabolomeAdultAmino AcidsAnimalsBiomarkersCarnitineCase-Control StudiesFemaleHumansMaleMiceMice, Inbred BALB CPsoriasisAmino AcidsBiomarkersCarnitineamino acidL-carnitinemetabolomicspsoriasisTh17

Identifiers

PMID33391503
PMCPMC7738860
OpenAlexW3094804619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.