Evidence map›Paper›PMID 33391491›Full record

ArticleTheranostics2021

Boiling histotripsy and in-situ CD40 stimulation improve the checkpoint blockade therapy of poorly immunogenic tumors.

Mohit Pratap Singh, Sri Nandhini Sethuraman, Craig Miller, Jerry Malayer, Ashish Ranjan

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  19. Overview of Therapeutic Ultrasound Applications and Safety Considerations: 2024 Update.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mohit Pratap SinghDepartment of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078.
Sri Nandhini SethuramanDepartment of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078.
Craig MillerDepartment of Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078.
Jerry MalayerDepartment of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078.
Ashish RanjanDepartment of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078.
Oklahoma State University · US

Funding

Novel focused ultrasound enhanced calreticulin-nanoparticle for immune primed melanoma immunotherapyR37CA239150 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI RANJAN, ASHISH · 2019 to 2025
$2.9M
NCI NIH HHS R37 CA239150
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCD40 AntigensCD8-Positive T-LymphocytesCombined Modality TherapyHigh-Intensity Focused Ultrasound AblationImmune Checkpoint InhibitorsMaleMelanoma, ExperimentalMiceMice, Inbred C57BLT-Lymphocytes, RegulatoryTumor MicroenvironmentCD40 AntigensImmune Checkpoint InhibitorsAnti-tumor immunityBoiling histotripsyCheckpoint blockadeCold tumorsαCD40

Identifiers

PMID33391491
PMCPMC7738858
OpenAlexW3095552012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.