Evidence map›Paper›PMID 33391481›Full record

ArticleTheranostics2021

Tumor cell-activated "Sustainable ROS Generator" with homogeneous intratumoral distribution property for improved anti-tumor therapy.

Junjie Liu, Xiu Zhao, Weimin Nie, Yue Yang, Chengcheng Wu, Wei Liu, Kaixiang Zhang, Zhenzhong Zhang, Jinjin Shi

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
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  10. Activation of autophagy byBioactive materials · 2023
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  14. MnTheranostics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Junjie LiuSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Xiu ZhaoSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Weimin NieSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Yue YangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Chengcheng WuSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Wei LiuSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Kaixiang ZhangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhenzhong ZhangSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Jinjin ShiSchool of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) holds a number of advantages for tumor therapy. However, its therapeutic efficiency is limited by non-sustainable reactive oxygen species (ROS) generation and heterogeneous distribution of photosensitizer (PS) in tumor. Herein, a "

Indexed as

Low-Level Light TherapyNanoparticlesPhotochemotherapyAnimalsApoptosisBreast NeoplasmsCell Line, TumorChlorophyllidesDrug CarriersGlutathioneGlutathione DisulfideHumansHyaluronic AcidHydrogen PeroxideHydroxyl RadicalManganese CompoundsChlorophyllidesDrug CarriersGlutathioneGlutathione DisulfideHyaluronic AcidHydrogen PeroxideHydroxyl RadicalManganese Compoundsmanganese oxideOxidesphytochlorinPorphyrinsRadiation-Sensitizing AgentsReactive Oxygen SpeciesSilicon DioxideSinglet OxygenGSH depletionhomogeneous tumor distributionsustainable ROS generationswitched on

Identifiers

PMID33391481
PMCPMC7681092
OpenAlexW3096812916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.