Evidence map›Paper›PMID 33391478›Full record

ArticleTheranostics2021

TDP-43 proteinopathy impairs mRNP granule mediated postsynaptic translation and mRNA metabolism.

Chia-En Wong, Lee-Way Jin, Yuan-Ping Chu, Wei-Yen Wei, Pei-Chuan Ho, Kuen-Jer Tsai

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  7. Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD.bioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Beyond the Synapse:International journal of molecular sciences · 2024
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Synaptic Dysfunction and Plasticity in Amyotrophic Lateral Sclerosis.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chia-En WongDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lee-Way JinDepartment of Pathology and Laboratory Medicine, UC Davis Medical Center, California, USA.
Yuan-Ping ChuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wei-Yen WeiInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Pei-Chuan HoInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Kuen-Jer TsaiInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
National Cheng Kung University · TW

Funding

UC Davis Alzheimer's Disease Core CenterP30AG010129 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI DECARLI, CHARLES · 1991 to 2020
$28.3M
NIA NIH HHS P30 AG010129
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDendritesDisease Models, AnimalDisks Large Homolog 4 ProteinDNA-Binding ProteinsFrontotemporal Lobar DegenerationGene Expression RegulationHEK293 CellsHumansMiceMice, TransgenicMicroscopyNeuronal PlasticityNeuronsPrimary Cell CultureProsencephalonDisks Large Homolog 4 ProteinDNA-Binding Proteinsmessenger ribonucleoproteinRibonucleoproteinsRNA, MessengerTARDBP protein, humanTardbp protein, mouselocal translationmRNP granulepostsynapticsuper-resolution microscopyTDP-43

Identifiers

PMID33391478
PMCPMC7681104
OpenAlexW3094797803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.