ArticleTheranostics2021
A role for intestinal alkaline phosphatase in preventing liver fibrosis.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- A role for curcumin in preventing liver fibrosis in animals: a systematic review and meta-analysis.Frontiers in pharmacology · 2024Pooled it
- The Relationship Between Obesity and Intestinal Alkaline Phosphatase: A Clinical and Biochemical Study.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2026Article
- The Gastrointestinal Barrier-Mechanisms of Barrier Dysfunction in Liver Cirrhosis and Spontaneous Bacterial Peritonitis.Biomedicines · 2026Review
- Phosphorylated Chemiluminescent Probe Based on Spiro-cyclobutyl-phenoxy-dioxetane for the In Situ Light-Activated Sensing of Alkaline Phosphatase.Analytical chemistry · 2026Article
- Genetic evidence for causal roles of circulating proteins on breast cancer susceptibility.iScience · 2026Article
- From gut to liver: Exploring the relationship between inflammatory bowel disease and metabolic dysfunction-associated steatotic liver disease.World journal of hepatology · 2025Review
- Polymer-enhanced peroxidase activity of ceria nanozyme for highly sensitive detection of alkaline phosphatase.Analytical and bioanalytical chemistry · 2024Article
- Alkaline phosphatase treatment of acute kidney injury-an update.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Review
- Fecal microbiota composition, serum metabolomics, and markers of inflammation in dogs fed a raw meat-based diet compared to those on a kibble diet.Frontiers in veterinary science · 2024Article
- Gut microbes combined with metabolomics reveal the protective effects of Qijia Rougan decoction against CClFrontiers in pharmacology · 2024Article
- Research Progress Regarding the Effect and Mechanism of Dietary Polyphenols in Liver Fibrosis.Molecules (Basel, Switzerland) · 2023Review
- Combi-Elasto Evaluation of the Degree of Liver Fibrosis in Children with Cholestatic Liver Disease.Diagnostics (Basel, Switzerland) · 2023Article
- Modulating phenylalanine metabolism by L. acidophilus alleviates alcohol-related liver disease through enhancing intestinal barrier function.Cell & bioscience · 2023Article
- Review
- Total flavonoids extracted fromFrontiers in pharmacology · 2023Article
- Article
- Implication of Echinochrome A in the Plasticity and Damage of Intestinal Epithelium.Marine drugs · 2022Article
- Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4.Clinical and molecular hepatology · 2022Article
- Protective Effect of Alkaline Phosphatase Supplementation on Infant Health.Foods (Basel, Switzerland) · 2022Review
- The Role of Gut-Derived Lipopolysaccharides and the Intestinal Barrier in Fatty Liver Diseases.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 2 countries.
Yang LiuDepartment of General Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, China.
Paul M CavallaroDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Byeong-Moo KimDivision of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Tao LiuDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Hongyan WangDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Florian KühnDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Fatemeh AdiliaghdamDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Enyu LiuDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Robin VasanDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Ehsan SamarbafzadehDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Matthew Z FarberDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Junhui LiDepartment of General Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, China.
Meng XuDepartment of General Surgery, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, China.
Vidisha MohadDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Michael ChoiDivision of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Richard A HodinDepartment of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, US.
Second Affiliated Hospital of Xi'an Jiaotong University · CNLudwig-Maximilians-Universität München · DE
Funding
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3MROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6MRESEARCH TRAINING IN ALIMENTARY TRACT SURGERYT32DK007754 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI HODIN, RICHARD A. · 1997 to 2025
$6.5MNIDDK NIH HHS P30 DK040561NIDDK NIH HHS P30 DK043351NIDDK NIH HHS T32 DK007754
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdultAlkaline PhosphataseAnimalsCarbon TetrachlorideCommon Bile DuctDisease Models, AnimalFecesFemaleGPI-Linked ProteinsHumansIleumIntestinesLigationLipopolysaccharidesLiver CirrhosisMaleAkp3 protein, mouseAlkaline PhosphataseALPI protein, humanCarbon TetrachlorideGPI-Linked ProteinsLipopolysaccharidesTight Junction ProteinsTlr4 protein, mouseToll-Like Receptor 4gut barrierintestinal alkaline phosphataseLiver fibrosisTLR4
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.