Evidence map›Paper›PMID 33391382›Full record

ArticleIranian journal of pathology2021

Variants of Genes Involved in Metabolism of Folate Among Patients with Breast Cancer: Association of

Zohreh Rahimi, Maryam Bozorgi Zarini, Ziba Rahimi, Ebrahim Shakiba, Asad Vaisi-Raygani, Mohammad Taher Moradi, Kheirolah Yari

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zohreh RahimiMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Maryam Bozorgi ZariniMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Ziba RahimiMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Ebrahim ShakibaDepartment of Clinical Biochemistry, Medical School, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Asad Vaisi-RayganiFertility and Infertility Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mohammad Taher MoradiMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Kheirolah YariMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Kermanshah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

objectiveBreast cancer (BC) is known to be the most prevalent cancer among women. One-carbon metabolism disturbance might play an important role in the etiology of BC. The present study aimed to investigate the thymidylate synthase (TYMS), 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), and methionine synthase reductase (MTRR) variants as good candidates for studying the role of genetic variants of folate metabolizing enzymes in the risk of BC.

methodsThe present case-control study includes 100 BC patients and 141 healthy females. The

resultsThe 3R allele of

conclusionWe observed that the

Indexed as

Breast cancerMetastasisMethionine synthaseMethionine synthase reductasePolymorphismThymidylate synthase

Identifiers

PMID33391382
PMCPMC7691710
OpenAlexW3100015170

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.