Evidence map›Paper›PMID 33391340›Full record

ArticleFrontiers in genetics2020

Using The Cancer Genome Atlas as an Inquiry Tool in the Undergraduate Classroom.

William Hankey, Nicholas Zanghi, Mackenzie M Crow, Whitney H Dow, Austin Kratz, Ashley M Robinson, Meaghan R Robinson, Verónica A Segarra

Abstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. A Bioinformatic Approach to Enhance Undergraduate Student Understanding of the Cancer-Immunity Cycle.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023
    Article
  2. Article
  3. Article
  4. Article
  5. Online Tools for Teaching Cancer Bioinformatics.Journal of microbiology & biology education · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

William HankeyDepartment of Pathology, Duke Cancer Center, Duke University, Durham, NC, United States.
Nicholas ZanghiDepartment of Biology, High Point University, High Point, NC, United States.
Mackenzie M CrowDepartment of Biology, High Point University, High Point, NC, United States.
Whitney H DowDepartment of Biology, High Point University, High Point, NC, United States.
Austin KratzDepartment of Chemistry, High Point University, High Point, NC, United States.
Ashley M RobinsonDepartment of Biology, High Point University, High Point, NC, United States.
Meaghan R RobinsonDepartment of Biology, High Point University, High Point, NC, United States.
Verónica A SegarraDepartment of Biology, High Point University, High Point, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Undergraduate students in the biomedical sciences are often interested in future health-focused careers. This presents opportunities for instructors in genetics, molecular biology, and cancer biology to capture their attention using lab experiences built around clinically relevant data. As biomedical science in general becomes increasingly dependent on high-throughput data, well-established scientific databases such as The Cancer Genome Atlas (TCGA) have become publicly available tools for medically relevant inquiry. The best feature of this database is that it bridges the molecular features of cancer to human clinical outcomes-allowing students to see a direct connection between the molecular sciences and their future professions. We have developed and tested a learning module that leverages the power of TCGA datasets to engage students to use the data to generate and test hypotheses and to apply statistical tests to evaluate significance.

Indexed as

bioinformaticscancercancer genomicsgenomicsundergraduate teaching and learning

Identifiers

PMID33391340
PMCPMC7772960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.