Evidence map›Paper›PMID 33391284›Full record

ArticleFrontiers in immunology2020

Pharmaco-Optogenetic Targeting of TRPC Activity Allows for Precise Control Over Mast Cell NFAT Signaling.

Bernadett Bacsa, Annarita Graziani, Denis Krivic, Patrick Wiedner, Roland Malli, Thomas Rauter, Oleksandra Tiapko, Klaus Groschner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bernadett BacsaGottfried-Schatz-Research-Center-Biophysics, Medical University of Graz, Graz, Austria.
Annarita GrazianiGottfried-Schatz-Research-Center-Biophysics, Medical University of Graz, Graz, Austria.
Denis KrivicGottfried-Schatz-Research-Center-Biophysics, Medical University of Graz, Graz, Austria.
Patrick WiednerGottfried-Schatz-Research-Center-Biophysics, Medical University of Graz, Graz, Austria.
Roland MalliGottfried-Schatz-Research-Center-Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
Thomas RauterGottfried-Schatz-Research-Center-Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.
Oleksandra TiapkoGottfried-Schatz-Research-Center-Biophysics, Medical University of Graz, Graz, Austria.
Klaus GroschnerGottfried-Schatz-Research-Center-Biophysics, Medical University of Graz, Graz, Austria.
Medical University of Graz · AT

Funding

Austrian Science Fund FWF W 1226
6 · The paper itself

Abstract

Canonical transient receptor potential (TRPC) channels are considered as elements of the immune cell Ca

Indexed as

AnimalsCalciumCalcium SignalingCell Line, TumorImmunityMast CellsNFATC Transcription FactorsOptogeneticsRatsRNA, MessengerSignal TransductionTRPC Cation ChannelsCalciumNFATC Transcription FactorsRNA, MessengerTRPC Cation Channelscanonical transient receptor potential channelsmast cellsNFAT nuclear translocationOptoBI-1opto-chemical immunomodulationphotopharmacology

Identifiers

PMID33391284
PMCPMC7775509
OpenAlexW3111750780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.