ArticleFrontiers in immunology2020
Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses.
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In one paragraph
Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 57 citations in OpenAlex.
- Extensive peripheral immunoglobulin repertoire analyses in people with multiple sclerosis reveal disease-specific signatures and distinct treatment effects of disease modifying drugs.Journal of neuroinflammation · 2026Article
- Immunophenotypic skewing of B cells toward IgD⁻CD27⁻IgG⁺ subtype and metabolic attenuation in colorectal cancer.Scientific reports · 2026Article
- The pathogenic role of double-negative B cells in autoimmune diseases.Frontiers in immunology · 2026Review
- Persistent Classical and Atypical Memory B Cells Underlie Heterogeneous Vaccine Responses in Ocrelizumab-Treated Multiple Sclerosis.bioRxiv : the preprint server for biology · 2025Article
- Decreased IgD- CD27- double negative B cells in Sjögren's disease correlated with disease activity index.Scientific reports · 2025Article
- JAK Inhibitors and B Cell Function: A Comparative Study of Their Impact on Plasma Cell Differentiation, Cytokine Production, and Naïve B Cell Activation.European journal of immunology · 2025Article
- B cell depletion as a therapeutic strategy for neuromyelitis optica spectrum disorder: rationale, evidence, and challenges.Frontiers in immunology · 2025Review
- High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance.Communications medicine · 2024Article
- Profiles of peripheral B cell subsets in a cohort of primary Sjögren's syndrome patients and their potential clinical significance.Journal of dental sciences · 2024Article
- Age-Related Alterations in Immune Function and Inflammation: Focus on Ischemic Stroke.Aging and disease · 2024Review
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- Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients.Acta neuropathologica · 2024Article
- Early B lymphocyte subsets in blood predict prognosis in sepsis.Frontiers in immunology · 2024Article
- Emerging insights into atypical B cells in pediatric chronic infectious diseases and immune system disorders: T(o)-bet on control of B-cell immune activation.The Journal of allergy and clinical immunology · 2024Review
- Altered B-Cell Expansion and Maturation in Draining Mesenteric Lymph Nodes of Inflamed Gut in Crohn's Disease.Cellular and molecular gastroenterology and hepatology · 2024Article
- Peripheral memory B cells in multiple sclerosis vs. double negative B cells in neuromyelitis optica spectrum disorder: disease driving B cell subsets during CNS inflammation.Frontiers in cellular neuroscience · 2024Review
- Pathogenic roles of follicular helper T cells in IgG4-related disease and implications for potential therapy.Frontiers in immunology · 2024Review
- Causal relationship between immune cells and Guillain-Barré syndrome: a Mendelian randomization study.Frontiers in neurology · 2024Article
- An extended SARS-CoV-2 mRNA vaccine prime-boost interval enhances B cell immunity with limited impact on T cells.iScience · 2023Article
- Neuron-binding antibody responses are associated with Black ethnicity in multiple sclerosis during natalizumab treatment.Brain communications · 2023Article
Corrections and comments
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Authors and funding
14 authors at 9 institutions in 2 countries.
Christoph RuschilDepartment of Neurology and Stroke, Eberhard-Karls University, Tübingen, Germany.
Gisela GabernetQuantitative Biology Center (QBiC), Eberhard-Karls University of Tübingen, Tübingen, Germany.
Gildas LepennetierDepartment of Neurology, Technische Universität München, Munich, Germany.
Simon HeumosQuantitative Biology Center (QBiC), Eberhard-Karls University of Tübingen, Tübingen, Germany.
Miriam KaminskiDepartment of Psychiatry and Psychotherapy, Charite Universitätsmedizin, Berlin, Germany.
Zsuzsanna HracskoDepartment of Internal Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.
Martin IrmlerInstitute of Experimental Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany.
Johannes BeckersInstitute of Experimental Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany.
Ulf ZiemannDepartment of Neurology and Stroke, Eberhard-Karls University, Tübingen, Germany.
Sven NahnsenQuantitative Biology Center (QBiC), Eberhard-Karls University of Tübingen, Tübingen, Germany.
Gregory P OwensDepartment of Biochemistry and Molecular Genetics, University of Colorado, Aurora, CO, United States.
Jeffrey L BennettDepartment of Neurology, Programs in Neuroscience and Immunology University of Colorado School of Medicine, Aurora, CO, United States.
Bernhard HemmerDepartment of Neurology, Technische Universität München, Munich, Germany.
Markus C KowarikDepartment of Neurology and Stroke, Eberhard-Karls University, Tübingen, Germany.
University of Tübingen · DEHelmholtz Zentrum München · DECharité - Universitätsmedizin Berlin · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEHertie Institute for Clinical Brain Research · DEMunich Cluster for Systems Neurology · DETechnical University of Munich · DEUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · US
Funding
Humoral Immunity, Astrocyte Injury, and Demyelination in Neuromyelitis OpticaR01EY022936 · NEI · UNIVERSITY OF COLORADO DENVER · PI BENNETT, JEFFREY L · 2013 to 2022
$3.8MNEI NIH HHS R01 EY022936
Abstract
Double negative (DN) (CD19
Indexed as
Cell ProliferationImmunogenicity, VaccineLymphocyte ActivationAdolescentAdultAgedAged, 80 and overAntibodies, ViralAntigens, CD19Antigens, CD20B-LymphocytesCase-Control StudiesCommunicable DiseasesEncephalitis Viruses, Tick-BorneFemaleHumansAntibodies, ViralAntigens, CD19Antigens, CD20CD19 molecule, humanInfluenza VaccinesTumor Necrosis Factor Receptor Superfamily, Member 7Viral Vaccinesautoimmune disordersB cellsdouble negative B cellsinfluenza vaccinationneuromyelitis optica spectrum disorderTBE vaccinationvaccination
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.